Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50314617 ((2S,6R)-4-((3,5-dimethylisoxazol-4-yl)methoxy)-2,6...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article PubMed | 43 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pfizer Global Research and Development Curated by ChEMBL | Assay Description Binding affinity to 5HT2C receptor | Bioorg Med Chem Lett 20: 2365-9 (2010) Article DOI: 10.1016/j.bmcl.2010.01.107 BindingDB Entry DOI: 10.7270/Q24M94QJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50314617 ((2S,6R)-4-((3,5-dimethylisoxazol-4-yl)methoxy)-2,6...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents | Article | n/a | n/a | n/a | n/a | 22 | n/a | n/a | n/a | n/a |
TBA | Assay Description Agonist activity at Homo sapiens (human) 5-HT2C receptor assessed as 5-HT-induced calcium mobilization by cell based assay | Citation and Details Article DOI: 10.1007/s00044-011-9615-3 BindingDB Entry DOI: 10.7270/Q2SF3028 | |||||||||||
More data for this Ligand-Target Pair |