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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 3A' and Ligand = 'BDBM50330467'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 3A


(Homo sapiens (Human))		BDBM50330467
PNG
(3-Amino-5-fluoro-2-[4-(4-quinolin-2-ylpiperazin-1-...)
Show SMILES Nn1c(CCCCN2CCN(CC2)c2ccc3ccccc3n2)nc2cccc(F)c2c1=O
Show InChI InChI=1S/C25H27FN6O/c26-19-7-5-9-21-24(19)25(33)32(27)23(29-21)10-3-4-13-30-14-16-31(17-15-30)22-12-11-18-6-1-2-8-20(18)28-22/h1-2,5-9,11-12H,3-4,10,13-17,27H2
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Article
PubMed
n/an/a 50.6n/an/an/an/an/an/a



ASKA Pharmaceutical Co, Ltd

Curated by ChEMBL


Assay Description
Displacement of [3H]BRL-43694 from human 5HT3 receptor expressed in HEK293 cells by liquid scintillation counting

J Med Chem 53: 7549-63 (2010)


Article DOI: 10.1021/jm1002292
BindingDB Entry DOI: 10.7270/Q27082D1
More data for this
Ligand-Target Pair