Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
72 kDa type IV collagenase (Homo sapiens (Human)) | BDBM12072 ((R)-[1-(4-Methoxybiphenyl-4-sulfonylamino)-2-methy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | 5 | -47.4 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
Istituto di Cristallografia | Assay Description Inhibition of the matrix metalloproteinases MMP-2, MMP-3, and MMP-8 has been determined by continuously monitoring the hydrolysis of the fluorescent ... | J Med Chem 49: 923-31 (2006) Article DOI: 10.1021/jm050787+ BindingDB Entry DOI: 10.7270/Q2348HM7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
72 kDa type IV collagenase (Homo sapiens (Human)) | BDBM12072 ((R)-[1-(4-Methoxybiphenyl-4-sulfonylamino)-2-methy...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 1.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Università "G. d'Annunzio" Curated by ChEMBL | Assay Description Inhibition of human recombinant MMP2 expressed in mouse myeloma cells | Bioorg Med Chem 15: 791-9 (2006) Article DOI: 10.1016/j.bmc.2006.10.047 BindingDB Entry DOI: 10.7270/Q2DR2V4T | |||||||||||
More data for this Ligand-Target Pair |