Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'ALK tyrosine kinase receptor' and Ligand = 'BDBM196893'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM196893 (US9212192, 56) Show SMILES COc1cc(ccc1Nc1nc(Cc2c(Cl)cccc2Cl)n2c(C)nnc2c1C(N)=O)N1CCNCC1 Show InChI InChI=1S/C25H26Cl2N8O2/c1-14-32-33-25-22(23(28)36)24(31-21(35(14)25)13-16-17(26)4-3-5-18(16)27)30-19-7-6-15(12-20(19)37-2)34-10-8-29-9-11-34/h3-7,12,29-30H,8-11,13H2,1-2H3,(H2,28,36)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	2	-49.7	n/a	n/a	n/a	n/a	n/a	7.4	25
AbbVie Inc. US Patent					Assay Description ALK kinase assays were conducted with the indicated final concentrations unless otherwise specified. In 384 well black plates (Axygen), 8 ul of compo...				US Patent US9212192 (2015) BindingDB Entry DOI: 10.7270/Q2D79971
					More data for this Ligand-Target Pair