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Found 1 hit Enz. Inhib. hit(s) with Target = 'ALK tyrosine kinase receptor' and Ligand = 'BDBM50344647'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
ALK tyrosine kinase receptor


(Homo sapiens (Human))		BDBM50344647
PNG
(8-(2-(diethylamino)ethoxy)-3-fluoro-6,6-dimethylbe...)
Show SMILES CCN(CC)CCOc1ccc2C(=O)c3c(oc4cc(F)ccc34)C(C)(C)c2c1
Show InChI InChI=1S/C24H26FNO3/c1-5-26(6-2)11-12-28-16-8-10-17-19(14-16)24(3,4)23-21(22(17)27)18-9-7-15(25)13-20(18)29-23/h7-10,13-14H,5-6,11-12H2,1-4H3
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KEGG

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Similars
Article
PubMed
n/an/a 850n/an/an/an/an/an/a



Chugai Pharmaceutical Co. Ltd.

Curated by ChEMBL


Assay Description
Inhibition of ALK assessed as biotin-EGPWLEEEEEAYGWMDF peptide phosphorylation by TR-FRET assay

Bioorg Med Chem Lett 21: 3788-93 (2011)

Checked by Author
Article DOI: 10.1016/j.bmcl.2011.04.020
BindingDB Entry DOI: 10.7270/Q2Q81DF2
More data for this
Ligand-Target Pair