BindingDB PrimarySearch

Found 11 hits Enz. Inhib. hit(s) with Target = 'ATP-citrate synthase' and Ligand = 'BDBM50066683'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
ATP-citrate synthase (Rattus norvegicus)	BDBM50066683 ((S)-2-((R)-8-(2,4-dichlorophenyl)-2-hydroxyoctyl)-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL					Assay Description Inhibitory activity was tested agianst rat ATP-Citrate Lyase (ACL) enzyme				J Med Chem 41: 3582-95 (1998) Article DOI: 10.1021/jm980091z BindingDB Entry DOI: 10.7270/Q2B8577D
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-citrate synthase (Rattus norvegicus)	BDBM50066683 ((S)-2-((R)-8-(2,4-dichlorophenyl)-2-hydroxyoctyl)-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL					Assay Description Inhibitory activity was tested agianst rat ATP-Citrate Lyase (ACL) enzyme				J Med Chem 41: 3582-95 (1998) Article DOI: 10.1021/jm980091z BindingDB Entry DOI: 10.7270/Q2B8577D
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-citrate synthase (Homo sapiens (Human))	BDBM50066683 ((S)-2-((R)-8-(2,4-dichlorophenyl)-2-hydroxyoctyl)-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	770	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL					Assay Description Inhibitory activity against human recombinant ATP-Citrate Lyase (ACL) enzyme				J Med Chem 41: 3582-95 (1998) Article DOI: 10.1021/jm980091z BindingDB Entry DOI: 10.7270/Q2B8577D
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-citrate synthase (Homo sapiens (Human))	BDBM50066683 ((S)-2-((R)-8-(2,4-dichlorophenyl)-2-hydroxyoctyl)-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	770	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL					Assay Description Inhibitory activity against human recombinant ATP-Citrate Lyase (ACL) enzyme				J Med Chem 41: 3582-95 (1998) Article DOI: 10.1021/jm980091z BindingDB Entry DOI: 10.7270/Q2B8577D
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-citrate synthase (Homo sapiens (Human))	BDBM50066683 ((S)-2-((R)-8-(2,4-dichlorophenyl)-2-hydroxyoctyl)-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pisa Curated by ChEMBL					Assay Description Inhibition of human ACLY				Eur J Med Chem 157: 1276-1291 (2018) Article DOI: 10.1016/j.ejmech.2018.09.001 BindingDB Entry DOI: 10.7270/Q2N0197R
University of Pisa Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-citrate synthase (Rattus norvegicus)	BDBM50066683 ((S)-2-((R)-8-(2,4-dichlorophenyl)-2-hydroxyoctyl)-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pisa Curated by ChEMBL					Assay Description Inhibition of rat ACLY				Eur J Med Chem 157: 1276-1291 (2018) Article DOI: 10.1016/j.ejmech.2018.09.001 BindingDB Entry DOI: 10.7270/Q2N0197R
University of Pisa Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-citrate synthase (Homo sapiens (Human))	BDBM50066683 ((S)-2-((R)-8-(2,4-dichlorophenyl)-2-hydroxyoctyl)-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Inhibition of human recombinant ACLY				J Med Chem 54: 5615-38 (2011) Article DOI: 10.1021/jm2005805 BindingDB Entry DOI: 10.7270/Q21N8261
Wayne State University Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-citrate synthase (Rattus norvegicus)	BDBM50066683 ((S)-2-((R)-8-(2,4-dichlorophenyl)-2-hydroxyoctyl)-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wayne State University Curated by ChEMBL					Assay Description Inhibition of rat liver ACLY				J Med Chem 54: 5615-38 (2011) Article DOI: 10.1021/jm2005805 BindingDB Entry DOI: 10.7270/Q21N8261
Wayne State University Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-citrate synthase (Homo sapiens (Human))	BDBM50066683 ((S)-2-((R)-8-(2,4-dichlorophenyl)-2-hydroxyoctyl)-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sinhgad College of Pharmacy Curated by ChEMBL					Assay Description Inhibition of human ATP citrate lyase				Bioorg Med Chem 15: 4674-99 (2007) Article DOI: 10.1016/j.bmc.2007.04.031 BindingDB Entry DOI: 10.7270/Q24J0FZ9
Sinhgad College of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-citrate synthase (Homo sapiens (Human))	BDBM50066683 ((S)-2-((R)-8-(2,4-dichlorophenyl)-2-hydroxyoctyl)-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL					Assay Description Inhibitory activity was tested agianst human recombinant ATP-Citrate Lyase (ACL) enzyme				J Med Chem 41: 3582-95 (1998) Article DOI: 10.1021/jm980091z BindingDB Entry DOI: 10.7270/Q2B8577D
SmithKline Beecham Pharmaceuticals Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
ATP-citrate synthase (Homo sapiens (Human))	BDBM50066683 ((S)-2-((R)-8-(2,4-dichlorophenyl)-2-hydroxyoctyl)-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human recombinant ATP-citrate lyase				Bioorg Med Chem Lett 17: 3208-11 (2007) Article DOI: 10.1016/j.bmcl.2007.03.017 BindingDB Entry DOI: 10.7270/Q27P8Z26
					More data for this Ligand-Target Pair