Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'ATP-sensitive inward rectifier potassium channel 1' and Ligand = 'BDBM50235199'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-sensitive inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM50235199 (CHEMBL4070123) Show SMILES Cc1c2COC(=O)c2ccc1[C@@H](O)CN1CCC2(CC1)CCN(CC2)c1ccc(cn1)C#N |r| Show InChI InChI=1S/C26H30N4O3/c1-18-20(3-4-21-22(18)17-33-25(21)32)23(31)16-29-10-6-26(7-11-29)8-12-30(13-9-26)24-5-2-19(14-27)15-28-24/h2-5,15,23,31H,6-13,16-17H2,1H3/t23-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
Merck& Co. Inc. Curated by ChEMBL					Assay Description In vitro 100 nM cortex affinity to displace [3H]- -pirenzepine providing a measure of muscarinic m1 receptor antagonist affinity				Bioorg Med Chem Lett 27: 1109-1114 (2017) Article DOI: 10.1016/j.bmcl.2016.10.032 BindingDB Entry DOI: 10.7270/Q2T43WC8
					More data for this Ligand-Target Pair