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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Acetyl-CoA carboxylase 2 (ACC2)' and Ligand = 'BDBM50314898'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Acetyl-CoA carboxylase 2 (ACC2)


(Homo sapiens (Human))
BDBM50314898
PNG
(5-methoxy-1'-(2-(pyridin-3-yl)-1H-benzo[d]imidazol...)
Show SMILES COc1cccc2OC3(CCN(CC3)C(=O)c3ccc4nc([nH]c4c3)-c3cccnc3)CC(=O)c12
Show InChI InChI=1S/C27H24N4O4/c1-34-22-5-2-6-23-24(22)21(32)15-27(35-23)9-12-31(13-10-27)26(33)17-7-8-19-20(14-17)30-25(29-19)18-4-3-11-28-16-18/h2-8,11,14,16H,9-10,12-13,15H2,1H3,(H,29,30)
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PC cid
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Article
PubMed
n/an/a 19n/an/an/an/an/an/a



Pfizer Global Research and Development

Curated by ChEMBL


Assay Description
Inhibition of human recombinant ACC2 expressed in CHO cells after 1 hr by fluorescence reader


Bioorg Med Chem Lett 20: 2383-8 (2010)


Article DOI: 10.1016/j.bmcl.2009.04.091
BindingDB Entry DOI: 10.7270/Q22N52DW
More data for this
Ligand-Target Pair