Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Activin receptor type-1B' and Ligand = 'BDBM280349'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Activin receptor type-1B (Homo sapiens (Human))	BDBM280349 ((S)-4-(2-(5-chloro-2-fluorophenyl)-5-(dimethylamin...) Show SMILES C[C@H](O)CNC(=O)c1cnccc1Nc1cc(ncc1N(C)C)-c1cc(Cl)ccc1F |r| Show InChI InChI=1S/C22H23ClFN5O2/c1-13(30)10-27-22(31)16-11-25-7-6-18(16)28-20-9-19(26-12-21(20)29(2)3)15-8-14(23)4-5-17(15)24/h4-9,11-13,30H,10H2,1-3H3,(H,27,31)(H,25,26,28)/t13-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	114	n/a	n/a	n/a	n/a	n/a	n/a
Medivation Technologies LLC US Patent					Assay Description Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...				US Patent US10030004 (2018) BindingDB Entry DOI: 10.7270/Q2QC05HQ
					More data for this Ligand-Target Pair
Activin receptor type-1B (Homo sapiens (Human))	BDBM280349 ((S)-4-(2-(5-chloro-2-fluorophenyl)-5-(dimethylamin...) Show SMILES C[C@H](O)CNC(=O)c1cnccc1Nc1cc(ncc1N(C)C)-c1cc(Cl)ccc1F |r| Show InChI InChI=1S/C22H23ClFN5O2/c1-13(30)10-27-22(31)16-11-25-7-6-18(16)28-20-9-19(26-12-21(20)29(2)3)15-8-14(23)4-5-17(15)24/h4-9,11-13,30H,10H2,1-3H3,(H,27,31)(H,25,26,28)/t13-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	114	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q24M98N9
					More data for this Ligand-Target Pair
Activin receptor type-1B (Homo sapiens (Human))	BDBM280349 ((S)-4-(2-(5-chloro-2-fluorophenyl)-5-(dimethylamin...) Show SMILES C[C@H](O)CNC(=O)c1cnccc1Nc1cc(ncc1N(C)C)-c1cc(Cl)ccc1F |r| Show InChI InChI=1S/C22H23ClFN5O2/c1-13(30)10-27-22(31)16-11-25-7-6-18(16)28-20-9-19(26-12-21(20)29(2)3)15-8-14(23)4-5-17(15)24/h4-9,11-13,30H,10H2,1-3H3,(H,27,31)(H,25,26,28)/t13-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	114	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details BindingDB Entry DOI: 10.7270/Q2W380HG
					More data for this Ligand-Target Pair
Activin receptor type-1B (Homo sapiens (Human))	BDBM280349 ((S)-4-(2-(5-chloro-2-fluorophenyl)-5-(dimethylamin...) Show SMILES C[C@H](O)CNC(=O)c1cnccc1Nc1cc(ncc1N(C)C)-c1cc(Cl)ccc1F |r| Show InChI InChI=1S/C22H23ClFN5O2/c1-13(30)10-27-22(31)16-11-25-7-6-18(16)28-20-9-19(26-12-21(20)29(2)3)15-8-14(23)4-5-17(15)24/h4-9,11-13,30H,10H2,1-3H3,(H,27,31)(H,25,26,28)/t13-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	114	n/a	n/a	n/a	n/a	n/a	n/a
Medivation Technologies LLC US Patent					Assay Description Compound of the invention were screened in an in vitro kinase assay against several members of the TGFβ family of Ser/Thr kinases. The kinases t...				US Patent US10501436 (2019) BindingDB Entry DOI: 10.7270/Q20867PH
					More data for this Ligand-Target Pair