BindingDB PrimarySearch

Found 8 hits Enz. Inhib. hit(s) with Target = 'Adenosine receptor A1' and Ligand = 'BDBM50224770'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Adenosine receptor A1 (BOVINE)	BDBM50224770 ((2R,3R,4R,5R)-2-(2-chloro-6-(cyclopentylamino)-9H-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Camerino Curated by ChEMBL					Assay Description Inhibitory activity at Adenosine A1 receptor by inhibition of [3H]CHA binding to bovine brain cortical membranes.				J Med Chem 41: 1708-15 (1998) Article DOI: 10.1021/jm9707737 BindingDB Entry DOI: 10.7270/Q2ZW1MKQ
Universit£ di Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (BOVINE)	BDBM50224770 ((2R,3R,4R,5R)-2-(2-chloro-6-(cyclopentylamino)-9H-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Camerino Curated by ChEMBL					Assay Description Displacement of [3H]CCPA from adenosine A1 receptor in bovine cortical membrane				Bioorg Med Chem 16: 336-53 (2008) Article DOI: 10.1016/j.bmc.2007.09.035 BindingDB Entry DOI: 10.7270/Q2T43TXM
Universit£ di Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (BOVINE)	BDBM50224770 ((2R,3R,4R,5R)-2-(2-chloro-6-(cyclopentylamino)-9H-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars		1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Adenosine receptor A1 (BOVINE)	BDBM50224770 ((2R,3R,4R,5R)-2-(2-chloro-6-(cyclopentylamino)-9H-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Camerino Curated by ChEMBL					Assay Description Displacement of [3H]DPCPX binding to adenosine A1 receptors of bovine cortical membranes				J Med Chem 48: 1550-62 (2005) Article DOI: 10.1021/jm049408n BindingDB Entry DOI: 10.7270/Q25X29PX
Universit£ di Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (Homo sapiens (Human))	BDBM50224770 ((2R,3R,4R,5R)-2-(2-chloro-6-(cyclopentylamino)-9H-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	3.37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Camerino Curated by ChEMBL					Assay Description Displacement of [3H]CCPA from human recombinant adenosine A1 receptor expressed in CHO cells				Bioorg Med Chem 16: 336-53 (2008) Article DOI: 10.1016/j.bmc.2007.09.035 BindingDB Entry DOI: 10.7270/Q2T43TXM
Universit£ di Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (GUINEA PIG)	BDBM50224770 ((2R,3R,4R,5R)-2-(2-chloro-6-(cyclopentylamino)-9H-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Camerino Curated by ChEMBL					Assay Description Displacement of [3H]CCPA from adenosine A1 receptor in pig cortical membrane				Bioorg Med Chem 16: 336-53 (2008) Article DOI: 10.1016/j.bmc.2007.09.035 BindingDB Entry DOI: 10.7270/Q2T43TXM
Universit£ di Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (BOVINE)	BDBM50224770 ((2R,3R,4R,5R)-2-(2-chloro-6-(cyclopentylamino)-9H-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	4.56E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Camerino Curated by ChEMBL					Assay Description Displacement of [3H]CGS21680 from adenosine A1 receptor in bovine striatum membrane				Bioorg Med Chem 16: 336-53 (2008) Article DOI: 10.1016/j.bmc.2007.09.035 BindingDB Entry DOI: 10.7270/Q2T43TXM
Universit£ di Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A1 (GUINEA PIG)	BDBM50224770 ((2R,3R,4R,5R)-2-(2-chloro-6-(cyclopentylamino)-9H-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Camerino Curated by ChEMBL					Assay Description Displacement of [3H]CGS21680 from adenosine A1 receptor in pig striatum membrane				Bioorg Med Chem 16: 336-53 (2008) Article DOI: 10.1016/j.bmc.2007.09.035 BindingDB Entry DOI: 10.7270/Q2T43TXM
Universit£ di Camerino Curated by ChEMBL					More data for this Ligand-Target Pair