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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Adenosine receptor A2b' and Ligand = 'BDBM50025687'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Adenosine receptor A2b


(Homo sapiens (Human))		BDBM50025687
PNG
(2-[4-(1,3-Diethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-...)
Show SMILES CCn1c2nc([nH]c2c(=O)n(CC)c1=O)-c1ccc(OCC(=O)Nc2ccc(C)cc2)cc1
Show InChI InChI=1S/C24H25N5O4/c1-4-28-22-20(23(31)29(5-2)24(28)32)26-21(27-22)16-8-12-18(13-9-16)33-14-19(30)25-17-10-6-15(3)7-11-17/h6-13H,4-5,14H2,1-3H3,(H,25,30)(H,26,27)
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PC cid
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Similars
PubMed
 1.78n/an/an/an/an/an/an/an/a



National Institute of Diabetes

Curated by ChEMBL


Assay Description
Antagonist activity against human A2B adenosine receptor expressed in HEK-293 cells uisng [3H]-ZM-241,385 or [125I]-IABOPX

J Med Chem 43: 1165-72 (2000)


BindingDB Entry DOI: 10.7270/Q2M044NW
More data for this
Ligand-Target Pair