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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Adenosylhomocysteinase' and Ligand = 'BDBM50023886'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Adenosylhomocysteinase


(Homo sapiens (Human))
BDBM50023886
PNG
(2-[2-(4-Amino-imidazo[4,5-c]pyridin-1-yl)-ethylide...)
Show SMILES [#7]-c1nccc2n(-[#6]\[#6]=[#6](/[#6]-[#8])-[#6]-[#8])cnc12
Show InChI InChI=1S/C11H14N4O2/c12-11-10-9(1-3-13-11)15(7-14-10)4-2-8(5-16)6-17/h1-3,7,16-17H,4-6H2,(H2,12,13)
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CHEMBL
PC cid
PC sid
UniChem
PubMed
166n/an/an/an/an/an/an/an/a



University of Kansas

Curated by ChEMBL


Assay Description
Inhibition against bovine-liver S-Adenosyl-homocysteine (AdoHcy) hydrolase


J Med Chem 31: 1729-38 (1988)


BindingDB Entry DOI: 10.7270/Q2HM5920
More data for this
Ligand-Target Pair
Adenosylhomocysteinase


(Mus musculus)
BDBM50023886
PNG
(2-[2-(4-Amino-imidazo[4,5-c]pyridin-1-yl)-ethylide...)
Show SMILES [#7]-c1nccc2n(-[#6]\[#6]=[#6](/[#6]-[#8])-[#6]-[#8])cnc12
Show InChI InChI=1S/C11H14N4O2/c12-11-10-9(1-3-13-11)15(7-14-10)4-2-8(5-16)6-17/h1-3,7,16-17H,4-6H2,(H2,12,13)
PDB
MMDB

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UniProtKB/SwissProt

B.MOAD
GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem
PubMed
n/an/a 1.10E+5n/an/an/an/an/an/a



University of Kansas

Curated by ChEMBL


Assay Description
Evaluated for the 50% inhibition of S-Adenosyl-homocysteine (AdoHcy) hydrolase L929 lysate from murine L-929 cells


J Med Chem 31: 1729-38 (1988)


BindingDB Entry DOI: 10.7270/Q2HM5920
More data for this
Ligand-Target Pair