Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase' and Ligand = 'BDBM309224'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM309224 ((3R,4S)-N-(4-fluoro-3-methylphenyl)-4-(4-fluorophe...) Show SMILES Cc1cc(N[C@H]2CN(C[C@@H]2c2ccc(F)cc2)S(=O)(=O)c2cn(C)cn2)ccc1F Show InChI InChI=1S/C21H22F2N4O2S/c1-14-9-17(7-8-19(14)23)25-20-11-27(30(28,29)21-12-26(2)13-24-21)10-18(20)15-3-5-16(22)6-4-15/h3-9,12-13,18,20,25H,10-11H2,1-2H3/t18-,20+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
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