Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase' and Ligand = 'BDBM309226'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM309226 ((3R,4S)-4-(4-fluorophenyl)-N-[4-fluoro-3-(pyrimidi...) Show SMILES Cn1cnc(c1)S(=O)(=O)N1C[C@H](Nc2ccc(F)c(c2)-c2cncnc2)[C@H](C1)c1ccc(F)cc1 Show InChI InChI=1S/C24H22F2N6O2S/c1-31-13-24(29-15-31)35(33,34)32-11-21(16-2-4-18(25)5-3-16)23(12-32)30-19-6-7-22(26)20(8-19)17-9-27-14-28-10-17/h2-10,13-15,21,23,30H,11-12H2,1H3/t21-,23+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	<10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
AbbVie Inc.; AbbVie Deutschland GmbH & Co. KG US Patent					Assay Description Radioligand binding assays using recombinant CHO cell membranes expressing human GlyT1: Radioligand binding to human GlyT1c transporter-expressing me...				US Patent US9656955 (2017) BindingDB Entry DOI: 10.7270/Q2Z60R48
					More data for this Ligand-Target Pair