Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase' and Ligand = 'BDBM271894'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase (Homo sapiens (Human))	BDBM271894 (US10065945, Example 6) Show SMILES C[C@@H](N1CCc2ccc(cc2C1)S(=O)(=O)Nc1noc(n1)-c1ccccc1)c1ccc(OCC(F)(F)F)nc1 |r| Show InChI InChI=1S/C26H24F3N5O4S/c1-17(20-8-10-23(30-14-20)37-16-26(27,28)29)34-12-11-18-7-9-22(13-21(18)15-34)39(35,36)33-25-31-24(38-32-25)19-5-3-2-4-6-19/h2-10,13-14,17H,11-12,15-16H2,1H3,(H,32,33)/t17-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.20	n/a	n/a	n/a	n/a	n/a	25
Merck Sharp & Dohme Corp. US Patent					Assay Description A solution of 1 M LiHMDS in THF (51.7 ml, 51.7 mmol) was added dropwise to a mixture of Intermediate 3 (7.5 g, 17.2 mmol) and 5-(tert-butyl)-4-methyl...				US Patent US10065945 (2018) BindingDB Entry DOI: 10.7270/Q24X59TJ
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