BindingDB PrimarySearch

Found 51 hits Enz. Inhib. hit(s) with Target = 'Alpha-1A adrenergic receptor' and Ligand = 'BDBM29568'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Alpha-1A adrenergic receptor (Dog)	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	0.0100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UnWersity of Misscuri Curated by PDSP K_i Database									J Pharmacol Exp Ther 241: 875-81 (1987) BindingDB Entry DOI: 10.7270/Q29885JF
UnWersity of Misscuri Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	0.0100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UnWersity of Misscuri Curated by PDSP K_i Database									J Pharmacol Exp Ther 241: 875-81 (1987) BindingDB Entry DOI: 10.7270/Q29885JF
UnWersity of Misscuri Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	0.0200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UnWersity of Misscuri Curated by PDSP K_i Database									J Pharmacol Exp Ther 241: 875-81 (1987) BindingDB Entry DOI: 10.7270/Q29885JF
UnWersity of Misscuri Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Dog)	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	0.0200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UnWersity of Misscuri Curated by PDSP K_i Database									J Pharmacol Exp Ther 241: 875-81 (1987) BindingDB Entry DOI: 10.7270/Q29885JF
UnWersity of Misscuri Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	0.0300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duke University Curated by PDSP K_i Database									J Pharmacol Exp Ther 272: 134-42 (1995) BindingDB Entry DOI: 10.7270/Q2ZC81CG
Duke University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	0.0400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Jagiellonian University Collegium Medicum Curated by ChEMBL					Assay Description Displacement of [3H]prazosin from human adrenergic alpha1A receptor expressed in CHO cells				Eur J Med Chem 92: 221-35 (2015) Article DOI: 10.1016/j.ejmech.2014.12.045 BindingDB Entry DOI: 10.7270/Q2Q241XV
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	0.0400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Adamed Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]prazosin from human recombinant alpha1A adrenoceptor expressed in CHO cells				J Med Chem 57: 4543-57 (2014) Article DOI: 10.1021/jm401895u BindingDB Entry DOI: 10.7270/Q2N29ZHX
Adamed Ltd. Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	0.0600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier, Centre de Recherches de Croissy Curated by PDSP K_i Database									Synapse 35: 79-95 (2000) Article DOI: 10.1002/(SICI)1098-2396(200002)35:2<79::AID-SYN1>3.0.CO;2-X BindingDB Entry DOI: 10.7270/Q2XK8D4N
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	0.0700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Inhibition of [3H]- prazosin binding against Alpha-1A adrenergic receptor from rat submaxillary gland				J Med Chem 42: 5181-7 (2000) BindingDB Entry DOI: 10.7270/Q23T9HZ0
Warner-Lambert Company Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	0.0700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duke University Curated by PDSP K_i Database									J Pharmacol Exp Ther 272: 134-42 (1995) BindingDB Entry DOI: 10.7270/Q2ZC81CG
Duke University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	0.0900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Clinic and Foundation Curated by PDSP K_i Database									Eur J Pharmacol 103: 197-204 (1984) Article DOI: 10.1016/0014-2999(84)90478-3 BindingDB Entry DOI: 10.7270/Q2WW7G5B
Mayo Clinic and Foundation Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	0.110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Clinic Jacksonville Curated by PDSP K_i Database									Psychopharmacology (Berl) 114: 559-65 (1994) Article DOI: 10.1007/BF02244985 BindingDB Entry DOI: 10.7270/Q25X27FZ
Mayo Clinic Jacksonville Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	0.120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duke University Curated by PDSP K_i Database									J Pharmacol Exp Ther 272: 134-42 (1995) BindingDB Entry DOI: 10.7270/Q2ZC81CG
Duke University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Institut de Recherches Servier, Centre de Recherches de Croissy Curated by PDSP K_i Database									Synapse 35: 79-95 (2000) Article DOI: 10.1002/(SICI)1098-2396(200002)35:2<79::AID-SYN1>3.0.CO;2-X BindingDB Entry DOI: 10.7270/Q2XK8D4N
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (CALF)	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.126	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Roche Bioscience Curated by ChEMBL					Assay Description In vitro for the displacement of [3H]prazosin binding to bovine Alpha-1A adrenergic receptor				J Med Chem 40: 2674-87 (1997) Checked by Author Article DOI: 10.1021/jm970166j BindingDB Entry DOI: 10.7270/Q2R78GD2
Roche Bioscience Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	0.150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Shanghai Institute of Pharmaceutical Industry Curated by ChEMBL					Assay Description Displacement of [3H]prazosin from alpha1-adrenoceptor (unknown origin) in cerebral cortex membranes after 60 mins by TopCount scintillation counting ...				Eur J Med Chem 144: 701-715 (2018) Article DOI: 10.1016/j.ejmech.2017.12.063 BindingDB Entry DOI: 10.7270/Q26D5WP7
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (CALF)	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	0.170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity against Alpha-1A adrenergic receptor from bovine clone				J Med Chem 38: 3415-44 (1995) BindingDB Entry DOI: 10.7270/Q20G3J6W
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Dublin Curated by PDSP K_i Database									J Med Chem 49: 501-10 (2006) Article DOI: 10.1021/jm0503751 BindingDB Entry DOI: 10.7270/Q29G5KC3
University of Dublin Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	0.210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Children's Medical Research Center, Tokyo Curated by PDSP K_i Database									Biochem Biophys Res Commun 195: 902-9 (1993) Article DOI: 10.1006/bbrc.1993.2130 BindingDB Entry DOI: 10.7270/Q2FQ9V30
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Toray Industries, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]prazosin from adrenergic alpha-1A receptor in rat submaxillary gland membranes				Bioorg Med Chem Lett 16: 4045-7 (2006) Article DOI: 10.1016/j.bmcl.2006.05.002 BindingDB Entry DOI: 10.7270/Q2514001
Toray Industries, Inc. Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (PIG)	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by PDSP K_i Database									Eur J Pharmacol 347: 301-9 (1998) Article DOI: 10.1016/s0014-2999(98)00104-6 BindingDB Entry DOI: 10.7270/Q2GT5KQK
Uppsala University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	0.270	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Synaptic Pharmaceutical Corporation Curated by ChEMBL					Assay Description Ability to displace [3H]prazosin from cloned human Alpha-1A adrenergic receptor				J Med Chem 38: 1579-81 (1995) BindingDB Entry DOI: 10.7270/Q25Q4WRJ
Synaptic Pharmaceutical Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	0.280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Mayo Foundation for Medical Education and Research and Mayo Clinic Curated by PDSP K_i Database									Life Sci 68: 29-39 (2000) Article DOI: 10.1016/s0024-3205(00)00911-5 BindingDB Entry DOI: 10.7270/Q2057DHP
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Compound was evaluated for its ability to displace [125I]-HEAT binding from rat Alpha-1A adrenergic receptor				J Med Chem 41: 1205-8 (1998) Article DOI: 10.1021/jm980053f BindingDB Entry DOI: 10.7270/Q2XG9Q72
Merck & Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	0.310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duke University Curated by PDSP K_i Database									J Pharmacol Exp Ther 272: 134-42 (1995) BindingDB Entry DOI: 10.7270/Q2ZC81CG
Duke University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by PDSP K_i Database									Naunyn Schmiedebergs Arch Pharmacol 325: 136-44 (1984) Article DOI: 10.1007/bf00506193 BindingDB Entry DOI: 10.7270/Q25B00Z5
TBA Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	0.320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Dublin Curated by PDSP K_i Database									J Med Chem 49: 501-10 (2006) Article DOI: 10.1021/jm0503751 BindingDB Entry DOI: 10.7270/Q29G5KC3
University of Dublin Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	0.330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duke University Curated by PDSP K_i Database									J Biol Chem 266: 6365-9 (1991) BindingDB Entry DOI: 10.7270/Q2X928SG
Duke University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (CALF)	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	0.370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Duke University Curated by PDSP K_i Database									J Biol Chem 266: 6365-9 (1991) BindingDB Entry DOI: 10.7270/Q2X928SG
Duke University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	0.390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck & Co. Curated by ChEMBL					Assay Description Compound was tested for binding affinity utilizing cloned receptor binding assays by using [125 I]HEAT as radioligand to the human Alpha-1A adrenergi...				J Med Chem 41: 1205-8 (1998) Article DOI: 10.1021/jm980053f BindingDB Entry DOI: 10.7270/Q2XG9Q72
Merck & Co. Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	0.510	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					Assay Description Binding affinity against Alpha-1A adrenergic receptor from human clone				J Med Chem 38: 3415-44 (1995) BindingDB Entry DOI: 10.7270/Q20G3J6W
SmithKline Beecham Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	0.580	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Synaptic Pharmaceutical Corporation Curated by ChEMBL					Assay Description Binding affinity was determined for the alpha-1A adrenergic receptor				J Med Chem 41: 5320-33 (1999) Article DOI: 10.1021/jm980506g BindingDB Entry DOI: 10.7270/Q2R78DCS
Synaptic Pharmaceutical Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	0.580	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Synaptic Pharmaceutical Corporation Curated by ChEMBL					Assay Description Binding affinity against human Alpha-1A adrenergic receptor				Bioorg Med Chem Lett 9: 2843-8 (1999) BindingDB Entry DOI: 10.7270/Q2NK3FJ2
Synaptic Pharmaceutical Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	0.580	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Università di Milano Curated by ChEMBL					Assay Description The compound was tested for binding affinity on [3H]- prazosin as specific ligand on Human cloned alpha-1A adrenergic receptor expressed in CHO cells				J Med Chem 42: 173-7 (1999) Article DOI: 10.1021/jm981006q BindingDB Entry DOI: 10.7270/Q22J6B05
Università di Milano Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article	0.588	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to adrenergic alpha1A receptor (unknown origin)				Citation and Details Article DOI: 10.1007/s00044-010-9379-1 BindingDB Entry DOI: 10.7270/Q2NG4THH
TBA					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	0.589	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Bologna Curated by ChEMBL					Assay Description Binding affinity measured in CHO cells expressing human cloned Alpha-1A adrenergic receptor expressed as pKi				J Med Chem 46: 4895-903 (2003) Article DOI: 10.1021/jm030952q BindingDB Entry DOI: 10.7270/Q2ZK5KDG
University of Bologna Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	0.589	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Alma Mater Studiorum-University of Bologna Curated by ChEMBL					Assay Description Displacement of [3H]prazosin from human alpha1A adrenoceptor expressed in CHO cell membranes after 30 mins				Eur J Med Chem 136: 259-269 (2017) Article DOI: 10.1016/j.ejmech.2017.05.003 BindingDB Entry DOI: 10.7270/Q2W95CQN
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article	0.589	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Binding affinity to adrenergic alpha1A receptor (unknown origin)				Citation and Details Article DOI: 10.1007/s00044-010-9379-1 BindingDB Entry DOI: 10.7270/Q2NG4THH
TBA					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Synaptic Pharmaceutical Corporation Curated by ChEMBL					Assay Description In vitro binding affinity against alpha-1A adrenergic receptor of human liver microsomes				J Med Chem 42: 4778-93 (1999) BindingDB Entry DOI: 10.7270/Q2930SCW
Synaptic Pharmaceutical Corporation Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PubMed	0.610	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Istituto Chimico Farmaceutico e Tossicologico Curated by ChEMBL					Assay Description Binding affinity towards human cloned alpha1A-adrenoceptor using [3H]-prazosin as radioligand				J Med Chem 44: 2403-10 (2001) BindingDB Entry DOI: 10.7270/Q2WS8SHW
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (PIG)	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.630	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by PDSP K_i Database									Eur J Pharmacol 347: 301-9 (1998) Article DOI: 10.1016/s0014-2999(98)00104-6 BindingDB Entry DOI: 10.7270/Q2GT5KQK
Uppsala University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (PIG)	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.630	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by PDSP K_i Database									Eur J Pharmacol 347: 301-9 (1998) Article DOI: 10.1016/s0014-2999(98)00104-6 BindingDB Entry DOI: 10.7270/Q2GT5KQK
Uppsala University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Homo sapiens (Human))	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	0.690	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Emory University Curated by PDSP K_i Database									J Pharmacol Exp Ther 302: 58-65 (2002) Article DOI: 10.1124/jpet.302.1.58 BindingDB Entry DOI: 10.7270/Q2PG1Q9R
Emory University Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (CALF)	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.724	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Camerino Curated by ChEMBL					Assay Description Compound was tested for binding affinity against cloned Alpha-1A adrenergic receptor from bovine brain using radioligand ([3H]prazosin) binding assay				J Med Chem 39: 4602-7 (1996) Article DOI: 10.1021/jm960510x BindingDB Entry DOI: 10.7270/Q29W0J6P
University of Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (CALF)	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.930	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
H. Lundbeck A/S Curated by ChEMBL					Assay Description Displacement of [3H]prazosin (0.3 nM) from bovine Alpha-1A adrenergic receptor expressed in BHK cells				J Med Chem 46: 265-83 (2003) Article DOI: 10.1021/jm020938y BindingDB Entry DOI: 10.7270/Q2TB17MV
H. Lundbeck A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	0.933	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Camerino Curated by ChEMBL					Assay Description Binding affinity against native Alpha-1A adrenergic receptor from rat hippocampus pretreated with chloroethylclonidine using radioligand ([3H]prazosi...				J Med Chem 39: 4602-7 (1996) Article DOI: 10.1021/jm960510x BindingDB Entry DOI: 10.7270/Q29W0J6P
University of Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.05	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Camerino Curated by ChEMBL					Assay Description Compound was tested for its binding affinity towards Alpha-1A adrenergic receptor using [3H]-prazosin from rat submaxillary gland				J Med Chem 41: 1557-60 (1998) Article DOI: 10.1021/jm970740r BindingDB Entry DOI: 10.7270/Q2N29W3Q
University of Camerino Curated by ChEMBL					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	5.71E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
NIDA Addiction Research Center Curated by PDSP K_i Database									Life Sci 45: 1821-9 (1989) Article DOI: 10.1016/0024-3205(89)90523-7 BindingDB Entry DOI: 10.7270/Q20Z71SN
					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Whitby Research, Inc. Curated by PDSP K_i Database									J Pharmacol Exp Ther 265: 227-36 (1993) BindingDB Entry DOI: 10.7270/Q23J3BGM
Whitby Research, Inc. Curated by PDSP K_i Database					More data for this Ligand-Target Pair
Alpha-1A adrenergic receptor (Rattus norvegicus (Rat))	BDBM29568 (CHEMBL2 \| PRAZOSIN \| PRAZOSIN HYDROCHLORIDE \| [3H]...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	0.254	n/a	n/a	n/a	n/a	n/a	n/a
Dipartimento di Scienze Farmaceutiche Curated by ChEMBL					Assay Description Displacement of [3H]prazosin from adrenergic alpha1A receptor in Wistar rat submaxillary gland after 60 mins				J Med Chem 52: 7397-409 (2009) Article DOI: 10.1021/jm900458r BindingDB Entry DOI: 10.7270/Q2MG7PJ4
Dipartimento di Scienze Farmaceutiche Curated by ChEMBL					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 51 total ) | Next | Last >>