BindingDB PrimarySearch

Found 6 hits Enz. Inhib. hit(s) with Target = 'Alpha-2A adrenergic receptor' and Ligand = 'BDBM34572'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM34572 (BRIMONIDINE \| CHEMBL844 \| MLS000069370 \| SMR000058...) Show SMILES Brc1c(NC2=NCCN2)ccc2nccnc12 \|t:4\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Allergan Pharmaceuticals Curated by ChEMBL					Assay Description Displacement of rauwolscine from human Alpha-2A adrenergic receptor expressed in CHO cells				J Med Chem 40: 18-23 (1997) Article DOI: 10.1021/jm9605142 BindingDB Entry DOI: 10.7270/Q2RV0MST
Allergan Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Alpha-2A adrenergic receptor (MOUSE)	BDBM34572 (BRIMONIDINE \| CHEMBL844 \| MLS000069370 \| SMR000058...) Show SMILES Brc1c(NC2=NCCN2)ccc2nccnc12 \|t:4\| Show InChI	PDB Reactome pathway UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	43.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Roche Bioscience Curated by PDSP K_i Database									Biochem Pharmacol 55: 1035-43 (1998) Article DOI: 10.1016/s0006-2952(97)00631-x BindingDB Entry DOI: 10.7270/Q2T72G01
Roche Bioscience Curated by PDSP K_i Database					More data for this Ligand-Target Pair				3D Structure (crystal)
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM34572 (BRIMONIDINE \| CHEMBL844 \| MLS000069370 \| SMR000058...) Show SMILES Brc1c(NC2=NCCN2)ccc2nccnc12 \|t:4\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	214	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Roche Bioscience Curated by PDSP K_i Database									Biochem Pharmacol 55: 1035-43 (1998) Article DOI: 10.1016/s0006-2952(97)00631-x BindingDB Entry DOI: 10.7270/Q2T72G01
Roche Bioscience Curated by PDSP K_i Database					More data for this Ligand-Target Pair				3D Structure (crystal)
Alpha-2A adrenergic receptor (PIG)	BDBM34572 (BRIMONIDINE \| CHEMBL844 \| MLS000069370 \| SMR000058...) Show SMILES Brc1c(NC2=NCCN2)ccc2nccnc12 \|t:4\| Show InChI	PDB Reactome pathway KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB PubMed	479	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Michigan Curated by PDSP K_i Database									J Pharmacol Exp Ther 294: 539-47 (2000) BindingDB Entry DOI: 10.7270/Q2TM78NR
University of Michigan Curated by PDSP K_i Database					More data for this Ligand-Target Pair				3D Structure (crystal)
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM34572 (BRIMONIDINE \| CHEMBL844 \| MLS000069370 \| SMR000058...) Show SMILES Brc1c(NC2=NCCN2)ccc2nccnc12 \|t:4\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB	n/a	n/a	n/a	n/a	0.617	n/a	n/a	n/a	n/a
TBA					Assay Description Alpha-2A adrenergic receptor agonistic potency as inhibition of forskolin-stimulated synthesis of cyclic adenosine monophosphate				Citation and Details BindingDB Entry DOI: 10.7270/Q2DV1N3J
TBA					More data for this Ligand-Target Pair				3D Structure (crystal)
Alpha-2A adrenergic receptor (Homo sapiens (Human))	BDBM34572 (BRIMONIDINE \| CHEMBL844 \| MLS000069370 \| SMR000058...) Show SMILES Brc1c(NC2=NCCN2)ccc2nccnc12 \|t:4\| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	n/a	n/a	4.10	n/a	n/a	n/a	n/a
Allergan Pharmaceuticals Curated by ChEMBL					Assay Description Effective concentration at Alpha-2A adrenergic receptor from CHO-C10 cells				J Med Chem 40: 18-23 (1997) Article DOI: 10.1021/jm9605142 BindingDB Entry DOI: 10.7270/Q2RV0MST
Allergan Pharmaceuticals Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)