Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Alpha-2A adrenergic receptor (Homo sapiens (Human)) | BDBM50070328 (CHEBI:8862 | Rilmenidine) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Patents Similars | 182 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Assay Description Binding affinity towards human Alpha-2A adrenergic receptor by the displacement of [3H]rauwolscine | Citation and Details BindingDB Entry DOI: 10.7270/Q2GQ70ZD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2A adrenergic receptor (Homo sapiens (Human)) | BDBM50070328 (CHEBI:8862 | Rilmenidine) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | 300 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Belgrade Curated by ChEMBL | Assay Description Displacement of [3H]RS-79948-197 from recombinant human alpha2A adrenoreceptor expressed in CHOK1 cell membrane by scintillation counting method | Bioorg Med Chem 24: 3174-83 (2016) Article DOI: 10.1016/j.bmc.2016.05.043 BindingDB Entry DOI: 10.7270/Q2NZ89J3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2A adrenergic receptor (Homo sapiens (Human)) | BDBM50070328 (CHEBI:8862 | Rilmenidine) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Patents Similars | n/a | n/a | n/a | n/a | 275 | n/a | n/a | n/a | n/a | |
TBA | Assay Description Agonistic activity towards human Alpha-2A adrenergic receptor was measured as ability to inhibit forskolin-stimulated synthesis of cyclic adenosine m... | Citation and Details BindingDB Entry DOI: 10.7270/Q2GQ70ZD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-2A adrenergic receptor (Homo sapiens (Human)) | BDBM50070328 (CHEBI:8862 | Rilmenidine) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 178 | n/a | n/a | n/a | n/a |
University of Belgrade Curated by ChEMBL | Assay Description Agonist activity at recombinant human alpha2A adrenoreceptor expressed in CHOK1 cell membrane incubated for 30 mins by [35S]GTPgammaS binding assay | Bioorg Med Chem 24: 3174-83 (2016) Article DOI: 10.1016/j.bmc.2016.05.043 BindingDB Entry DOI: 10.7270/Q2NZ89J3 | |||||||||||
More data for this Ligand-Target Pair |