Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Alpha-glucosidase MAL12' and Ligand = 'BDBM181061'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-glucosidase MAL12 (Saccharomyces cerevisiae)	BDBM181061 ((E)-N'-(3,5-Di-tert-butyl-2-hydroxybenzylidene...) Show SMILES CC(C)(C)c1cc(\C=N\NC(=O)c2nc(cs2)-c2cc3ccccc3oc2=O)c(O)c(c1)C(C)(C)C Show InChI InChI=1S/C28H29N3O4S/c1-27(2,3)18-11-17(23(32)20(13-18)28(4,5)6)14-29-31-24(33)25-30-21(15-36-25)19-12-16-9-7-8-10-22(16)35-26(19)34/h7-15,32H,1-6H3,(H,31,33)/b29-14+	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.02E+4	n/a	n/a	n/a	n/a	6.8	n/a
Jishou University					Assay Description The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed by u...				Bioorg Chem 65: 167-74 (2016) Article DOI: 10.1016/j.bioorg.2016.03.001 BindingDB Entry DOI: 10.7270/Q2445K8R
					More data for this Ligand-Target Pair