Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Alpha-glucosidase MAL12 (Saccharomyces cerevisiae) | BDBM50333465 ((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 3.83E+4 | n/a | n/a | n/a | n/a | 6.8 | 37 |
COMSATS Institute of Information Technology, Lahore 54000, Pakistan | Assay Description Reaction mixture (100 µL) contained 70 µL 50 mM Na2HPO4 buffer, pH 6.8, 10 µL test compound (0.5 mM), followed by the addition of 10 &... | Bioorg Chem 54: 96-104 (2014) Article DOI: 10.1016/j.bioorg.2014.05.003 BindingDB Entry DOI: 10.7270/Q2NG4P8Q | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-glucosidase MAL12 (Saccharomyces cerevisiae) | BDBM50333465 ((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 1.09E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Universidade Federal do Rio de Janeiro Curated by ChEMBL | Assay Description Inhibition of yeast alpha-glucosidase MAL12 assessed as inhibition of p-nitrophenol release by spectrophotometry | J Med Chem 53: 2364-75 (2010) Article DOI: 10.1021/jm901265h BindingDB Entry DOI: 10.7270/Q20R9QC7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-glucosidase MAL12 (Saccharomyces cerevisiae) | BDBM50333465 ((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 2.30E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
SRTM University, Nanded, Maharashtra, 431606, India; Department of Molecular Biotechnology, College of Life and Environmental Sciences, Konkuk University, Seoul, 143-701, South Korea. | Assay Description The assay was performed using isolated phenolics from maize, and inhibition was determined according to previously described method. | Chem Biol Drug Des 83: 119-25 (2014) Article DOI: 10.1111/cbdd.12205 BindingDB Entry DOI: 10.7270/Q2Z89B2H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Alpha-glucosidase MAL12 (Saccharomyces cerevisiae) | BDBM50333465 ((2R,3R,4R,5R,6R)-5-((2R,3R,4R,5S,6R)-5-((2R,3R,4S,...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Similars | Article PubMed | n/a | n/a | 8.40E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Hazara University | Assay Description 10 µL of test samples (5 mg/mL DMSO solution) were reconstituted in 100 µL of 100 mM-phosphate buffer (pH6.8) in 96-well microplate and incubated wit... | Bioorg Chem 60: 42-8 (2015) Article DOI: 10.1016/j.bioorg.2015.03.005 BindingDB Entry DOI: 10.7270/Q2DR2T7R | |||||||||||
More data for this Ligand-Target Pair |