Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3' and Ligand = 'BDBM50447936'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 (Homo sapiens (Human))	BDBM50447936 (CHEMBL3114996) Show SMILES Cc1[nH]n(-c2nc3ccccc3[nH]2)c(=O)c1Cc1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C18H14Cl2N4O/c1-10-12(8-11-6-7-13(19)14(20)9-11)17(25)24(23-10)18-21-15-4-2-3-5-16(15)22-18/h2-7,9,23H,8H2,1H3,(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Hyogo University of Health Science Curated by ChEMBL					Assay Description Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysis				Bioorg Med Chem Lett 24: 1071-4 (2014) Article DOI: 10.1016/j.bmcl.2014.01.008 BindingDB Entry DOI: 10.7270/Q2FF3TVD
					More data for this Ligand-Target Pair