Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3' and Ligand = 'BDBM50447954'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 (Homo sapiens (Human))	BDBM50447954 (CHEMBL3115012) Show SMILES Cc1[nH]n(-c2nc3ccc(C)cc3[nH]2)c(=O)c1Cc1ccc(cc1)C(F)(F)F Show InChI InChI=1S/C20H17F3N4O/c1-11-3-8-16-17(9-11)25-19(24-16)27-18(28)15(12(2)26-27)10-13-4-6-14(7-5-13)20(21,22)23/h3-9,26H,10H2,1-2H3,(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	570	n/a	n/a	n/a	n/a	n/a	n/a
Hyogo University of Health Science Curated by ChEMBL					Assay Description Inhibition of demethylase activity of PCA-1 (unknown origin) using 3-methyl cytosine oligo DNA as substrate after 1 hr by RT-PCR analysis				Bioorg Med Chem Lett 24: 1071-4 (2014) Article DOI: 10.1016/j.bmcl.2014.01.008 BindingDB Entry DOI: 10.7270/Q2FF3TVD
					More data for this Ligand-Target Pair