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| Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet  | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 9.70E+3 | -28.6 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
University of Pavia | Assay Description MAO A and MAO B activities were determined spectrophotometrically at 316 nm and 250 nm using kynuramine and benzylamine as substrates, respectively. ... | J Med Chem 48: 8148-54 (2005) Article DOI: 10.1021/jm0506266 BindingDB Entry DOI: 10.7270/Q2T151WC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | 9.70E+3 | -28.6 | n/a | n/a | n/a | n/a | n/a | 7.5 | 25 |
Emory University | Assay Description MAO A and MAO B activities were determined spectrophotometrically at 316 nm and 250 nm using kynuramine and benzylamine as substrates, respectively. ... | J Med Chem 47: 1760-6 (2004) Article DOI: 10.1021/jm0310885 BindingDB Entry DOI: 10.7270/Q2P8494M | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Rattus norvegicus (rat)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
A* STAR (Agency of Science, Technology and Research) Curated by ChEMBL | Assay Description Inhibition of rat brain MAO-A in nuclei-free homogenates using [14C]hydroxytryptamine substrate after 20 mins by liquid scintillation counting | J Med Chem 58: 1400-19 (2015) Article DOI: 10.1021/jm501722s BindingDB Entry DOI: 10.7270/Q2V989R3 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human MAO-A | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112265 BindingDB Entry DOI: 10.7270/Q2W099J0 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | US Patent | n/a | n/a | 410 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA US Patent | Assay Description MAO-A and MAO-B activity was measured using radioactive substrates. The substrate for MAO-A was 5 HT and for MAO-B was PEA. When measuring the activi... | US Patent US9034303 (2015) BindingDB Entry DOI: 10.7270/Q20Z722N | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Rattus norvegicus (rat)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 410 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of MAO-A in rat brain using [14C]-5-hydroxytryptamine creatinine disulfate as substrate preincubated for 60 mins followed by substrate add... | J Med Chem 62: 8881-8914 (2019) Article DOI: 10.1021/acs.jmedchem.9b00017 BindingDB Entry DOI: 10.7270/Q27084PF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 410 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bologna Curated by ChEMBL | Assay Description Inhibition of MAOA | J Med Chem 51: 347-72 (2008) Article DOI: 10.1021/jm7009364 BindingDB Entry DOI: 10.7270/Q25B039W | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Rattus norvegicus (rat)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 412 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of rat brain MAO-A using [14C]-5- hydroxytryptamine creatinine disulphate substrate after 30 mins | J Med Chem 57: 6679-703 (2014) Article DOI: 10.1021/jm500729a BindingDB Entry DOI: 10.7270/Q2HT2R0D | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Rattus norvegicus (rat)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 422 | n/a | n/a | n/a | n/a | n/a | n/a |
NTZ Lab Ltd. Curated by ChEMBL | Assay Description Inhibition of Sprague-Dawley rat liver MAO-A using p-tyramine as substrate preincubated for 15 mins and measured after 45 mins by resorufin-based flu... | Eur J Med Chem 162: 793-809 (2019) Article DOI: 10.1016/j.ejmech.2018.11.009 BindingDB Entry DOI: 10.7270/Q26Q21ND | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 587 | n/a | n/a | n/a | n/a | n/a | n/a |
Sichuan University Curated by ChEMBL | Assay Description Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cells using kynuramine as substrate after 30 mins by fluorescence ... | Bioorg Med Chem 26: 1102-1115 (2018) Article DOI: 10.1016/j.bmc.2018.01.030 BindingDB Entry DOI: 10.7270/Q2MW2KRT | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 587 | n/a | n/a | n/a | n/a | n/a | n/a |
Chinese Academy of Sciences Curated by ChEMBL | Assay Description Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cells using kynuramine as substrate after 30 mins by fluorescence ... | Eur J Med Chem 183: (2019) Article DOI: 10.1016/j.ejmech.2019.111737 BindingDB Entry DOI: 10.7270/Q24J0JCX | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 587 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanyang Normal University Curated by ChEMBL | Assay Description Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cells using kynuramine as substrate incubated for 30 mins by fluor... | Eur J Med Chem 180: 238-252 (2019) Article DOI: 10.1016/j.ejmech.2019.07.021 BindingDB Entry DOI: 10.7270/Q2GH9N9F | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 587 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human recombinant MAO-A by multimode plate reader assay | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113310 BindingDB Entry DOI: 10.7270/Q28G8QGX | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 620 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanyang Normal University Curated by ChEMBL | Assay Description Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cells using kynuramine as substrate measured after 30 mins by fluo... | Eur J Med Chem 178: 726-739 (2019) Article DOI: 10.1016/j.ejmech.2019.06.026 BindingDB Entry DOI: 10.7270/Q2668HJZ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 630 | n/a | n/a | n/a | n/a | n/a | n/a |
Guizhou Medical University Curated by ChEMBL | Assay Description Inhibition of human recombinant MAO-A using kynuramine as substrate measured after 30 mins by fluorimetric assay | Bioorg Med Chem Lett 29: (2019) Article DOI: 10.1016/j.bmcl.2019.126625 BindingDB Entry DOI: 10.7270/Q2KD2286 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 680 | n/a | n/a | n/a | n/a | n/a | n/a |
NTZ Lab Ltd. Curated by ChEMBL | Assay Description Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI-TN-5B1-4 insect cells assessed as decrease in H2O2 production using p-tyr... | Eur J Med Chem 179: 404-422 (2019) Article DOI: 10.1016/j.ejmech.2019.06.041 BindingDB Entry DOI: 10.7270/Q2VT1WFM | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 680 | n/a | n/a | n/a | n/a | n/a | n/a |
NTZ Lab Ltd. Curated by ChEMBL | Assay Description Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI-TN-5B1-4 insect cells using p-tyramine as substrate preincubated for 15 m... | Eur J Med Chem 162: 793-809 (2019) Article DOI: 10.1016/j.ejmech.2018.11.009 BindingDB Entry DOI: 10.7270/Q26Q21ND | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
Sun Yat-sen University Curated by ChEMBL | Assay Description Inhibition of human recombinant MAOA assessed as H2O2 production by Amplex Red reagent-based assay | J Med Chem 55: 8483-92 (2012) Article DOI: 10.1021/jm300978h BindingDB Entry DOI: 10.7270/Q29Z962V | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 710 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Sichuan University | Assay Description Recombinant human MAO-A and MAO-B (5 mg/mL) were purchased from Sigma-Aldrich, pre-aliquoted and stored at -80 °C. Solutions of test compounds we... | Bioorg Chem 71: 305-314 (2017) Article DOI: 10.1016/j.bioorg.2017.02.016 BindingDB Entry DOI: 10.7270/Q2X9295T | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 710 | n/a | n/a | n/a | n/a | n/a | n/a |
Sichuan University Curated by ChEMBL | Assay Description Inhibition of recombinant human MAO-A using kynuramine as substrate after 30 mins by fluorescence assay | Bioorg Med Chem Lett 27: 718-722 (2017) Article DOI: 10.1016/j.bmcl.2017.01.050 BindingDB Entry DOI: 10.7270/Q2JM2CX6 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 710 | n/a | n/a | n/a | n/a | n/a | n/a |
Seoul National University Curated by ChEMBL | Assay Description Irreversible inhibition of human cerebral cortex MAO-A using [14C]-5-hydroxytryptamine creatinine disulphate as substrate pretreated for 60 mins foll... | Eur J Med Chem 130: 365-378 (2017) Article DOI: 10.1016/j.ejmech.2017.02.059 BindingDB Entry DOI: 10.7270/Q2K076J6 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 710 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Bonn Curated by ChEMBL | Assay Description Inhibition of human brain MAO-A using [14C]-5- hydroxytryptamine creatinine disulphate substrate after 30 mins | J Med Chem 57: 6679-703 (2014) Article DOI: 10.1021/jm500729a BindingDB Entry DOI: 10.7270/Q2HT2R0D | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 712 | n/a | n/a | n/a | n/a | n/a | n/a |
Guizhou Medical University Curated by ChEMBL | Assay Description Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cells using kynuramine as substrate measured after 30 mins by fluo... | Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115400 BindingDB Entry DOI: 10.7270/Q26W9FNR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 750 | n/a | n/a | n/a | n/a | n/a | n/a |
Institute of Materia Medica Curated by ChEMBL | Assay Description Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cells using p-tyramine as substrate preincubated for 60 mins follo... | Eur J Med Chem 173: 203-212 (2019) Article DOI: 10.1016/j.ejmech.2019.04.016 BindingDB Entry DOI: 10.7270/Q2BC42V2 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 830 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human MAOA using kynuramine as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins... | Citation and Details Article DOI: 10.1016/j.bmc.2021.116074 BindingDB Entry DOI: 10.7270/Q2HX1HBN | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.01E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Hefei University of Technology Curated by ChEMBL | Assay Description Inhibition of recombinant human MAO-A using p-tyramine as substrate preincubated for 15 mins followed by substrate addition measured over 15 mins by ... | Eur J Med Chem 145: 588-593 (2018) Article DOI: 10.1016/j.ejmech.2018.01.029 BindingDB Entry DOI: 10.7270/Q2JD50CJ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.02E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Guizhou Medical University Curated by ChEMBL | Assay Description Inhibition of recombinant human MAOA expressed in baculovirus infected in BTI cells using kynuramine as substrate after 30 mins by fluorescence based... | Bioorg Med Chem 28: (2020) Article DOI: 10.1016/j.bmc.2020.115374 BindingDB Entry DOI: 10.7270/Q24T6NXC | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.42E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sichuan University Curated by ChEMBL | Assay Description Inhibition of recombinant human MAO-A using kynuramine as substrate after 30 mins by fluorescence assay | Bioorg Med Chem 26: 1885-1895 (2018) Article DOI: 10.1016/j.bmc.2018.02.037 BindingDB Entry DOI: 10.7270/Q2J67KKZ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.42E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sichuan University Curated by ChEMBL | Assay Description Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cells using kynuramine as substrate incubated for 30 mins by fluor... | Eur J Med Chem 126: 762-775 (2017) Article DOI: 10.1016/j.ejmech.2016.12.009 BindingDB Entry DOI: 10.7270/Q2NG4SW1 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.42E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sichuan University Curated by ChEMBL | Assay Description Inhibition of recombinant human MAO-A expressed in baculovirus infected High 5 insect cells using kynuramine as substrate incubated for 30 mins by sp... | Bioorg Med Chem 25: 1030-1041 (2017) Article DOI: 10.1016/j.bmc.2016.12.013 BindingDB Entry DOI: 10.7270/Q2PR7XZS | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.42E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sichuan University Curated by ChEMBL | Assay Description Inhibition of human recombinant MAO-A using kynuramine as substrate after 30 mins by fluorescence spectrophotometry | Bioorg Med Chem 24: 2342-51 (2016) Article DOI: 10.1016/j.bmc.2016.04.012 BindingDB Entry DOI: 10.7270/Q21N8316 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.42E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sichuan University Curated by ChEMBL | Assay Description Inhibition of human recombinant MAO-A using kynuramine as substrate measured after 30 mins by fluorescence assay | Bioorg Med Chem 25: 714-726 (2017) Article DOI: 10.1016/j.bmc.2016.11.048 BindingDB Entry DOI: 10.7270/Q21C1ZVW | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.56E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
College of Chemistry and Pharmaceutical Engineering, Nanyang Normal University, Nanyang 473061, China. Electronic address: sangzhipei@126.com. Curated by ChEMBL | Assay Description Inhibition of human recombinant MAO-A expressed in baculovirus infected BTI insect cells using kynuramine as substrate after 30 mins by fluorescence ... | Bioorg Med Chem Lett 27: 5053-5059 (2017) Article DOI: 10.1016/j.bmcl.2017.09.055 BindingDB Entry DOI: 10.7270/Q22J6F9F | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
College of Chemistry and Pharmaceutical Engineering, Nanyang Normal University, Nanyang 473061, China. Electronic address: sangzhipei@126.com. Curated by ChEMBL | Assay Description Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cells using kynuramine as substrate after 30 mins by fluorescence ... | Bioorg Med Chem 25: 3006-3017 (2017) Article DOI: 10.1016/j.bmc.2017.03.070 BindingDB Entry DOI: 10.7270/Q2F76G04 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.13E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
College of Chemistry and Pharmaceutical Engineering, Nanyang Normal University, Nanyang 473061, China. Electronic address: sangzhipei@126.com. Curated by ChEMBL | Assay Description Inhibition of recombinant human MAO-A using kynuramine as substrate after 30 mins by fluorescence method | Bioorg Med Chem Lett 27: 5046-5052 (2017) Article DOI: 10.1016/j.bmcl.2017.09.057 BindingDB Entry DOI: 10.7270/Q2XS5XTR | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.34E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI-TN- 5B1-4 insect cells using kynuramine as substrate preincubated for 10 ... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00510 BindingDB Entry DOI: 10.7270/Q2N87FH1 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.61E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Sichuan University Curated by ChEMBL | Assay Description Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cells using kynuramine as substrate after 30 mins by fluorimetric ... | Bioorg Med Chem 25: 1997-2009 (2017) Article DOI: 10.1016/j.bmc.2017.02.027 BindingDB Entry DOI: 10.7270/Q2Q81GBJ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 3.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Porto Curated by ChEMBL | Assay Description Inhibition of human microsomal MAO-A expressed in baculovirus infected BTI-TN-5B1-4 cells assessed as reduction in 4-hydroxyquinoline formation using... | Eur J Med Chem 185: (2020) Article DOI: 10.1016/j.ejmech.2019.111770 BindingDB Entry DOI: 10.7270/Q21N84DJ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.42E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Citation and Details Article DOI: 10.1016/j.bmcl.2022.128917 BindingDB Entry DOI: 10.7270/Q2736VW3 | ||||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 1.64E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Santiago de Compostela Curated by ChEMBL | Assay Description Inhibition of human recombinant microsomal MAO-A expressed in baculovirus infected BTI-TN-5B1-4 cells using p-tyramine as substrate assessed as produ... | Eur J Med Chem 63: 151-61 (2013) Article DOI: 10.1016/j.ejmech.2013.02.009 BindingDB Entry DOI: 10.7270/Q2TH8QM1 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.95E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of human recombinant microsomal MAO-A expressed in baculovirus-infected BTI-TN-5B1-4 cells assessed as inhibition of H2O2 production using... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112282 BindingDB Entry DOI: 10.7270/Q29P35CF | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.95E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI-TN-5B1-4 insect cells using p-tyramine as substrate preincubated for 15 m... | Citation and Details Article DOI: 10.1016/j.ejmech.2020.112911 BindingDB Entry DOI: 10.7270/Q2RR22XQ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.95E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Ljubljana Curated by ChEMBL | Assay Description Inhibition of recombinant human microsomal MAOA expressed in baculovirus infected BTI insect cells using p-tyramine as substrate preincubated for 15 ... | J Med Chem 63: 1361-1387 (2020) Article DOI: 10.1021/acs.jmedchem.9b01886 BindingDB Entry DOI: 10.7270/Q2X92FKV | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 4.97E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
State Key Laboratory of Natural Medicines, Department of Natural Medicinal Chemistry, China Pharmaceutical University, 24 Tong Jia Xiang, Nanjing 210009, People's Republic of China. Curated by ChEMBL | Assay Description Inhibition of recombinant human MAO-A expressed in baculovirus infected BTI insect cells using p-tyramine as substrate pretreated for 15 mins followe... | Bioorg Med Chem 25: 3815-3826 (2017) Article DOI: 10.1016/j.bmc.2017.05.027 BindingDB Entry DOI: 10.7270/Q2BG2RH4 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 5.07E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
China Pharmaceutical University Curated by ChEMBL | Assay Description Inhibition of recombinant human MAO-A using p-tyramine as substrate assessed as decrease in H2O2 production incubated for 15 mins by fluorimetric met... | Bioorg Med Chem 24: 5929-5940 (2016) Article DOI: 10.1016/j.bmc.2016.09.050 BindingDB Entry DOI: 10.7270/Q2FN1854 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 5.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Porto Curated by ChEMBL | Assay Description Inhibition of human microsomal MAO-A expressed in recombinant baculovirus infected insect BTI-TN-5B1-4 cells assessed as reduction in H2O2 production... | J Med Chem 59: 5879-93 (2016) Article DOI: 10.1021/acs.jmedchem.6b00527 BindingDB Entry DOI: 10.7270/Q2X92FSJ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 5.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
CIQUP/Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto , 4169-007 Porto, Portugal. Curated by ChEMBL | Assay Description Inhibition of human recombinant microsomal MAOA expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate assessed as decre... | J Med Chem 60: 7206-7212 (2017) Article DOI: 10.1021/acs.jmedchem.7b00918 BindingDB Entry DOI: 10.7270/Q23B62KQ | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 5.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Porto Curated by ChEMBL | Assay Description Inhibition of human recombinant microsomal MAOA expressed in baculovirus infected BTI-TN-5B1- 4 cells using p-tyramine as substrate assessed as decre... | Eur J Med Chem 158: 781-800 (2018) Article DOI: 10.1016/j.ejmech.2018.07.056 BindingDB Entry DOI: 10.7270/Q2F192DM | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Rattus norvegicus (rat)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 4.01E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Hainan Normal University Curated by ChEMBL | Assay Description Inhibition of rat MAOA using 5-hydroxytryptamine as substrate pretreated for 1200 secs followed by substrate addition and measured after 3600 secs | Bioorg Med Chem 26: 4863-4870 (2018) Article DOI: 10.1016/j.bmc.2018.08.024 BindingDB Entry DOI: 10.7270/Q2319ZJ2 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
| Amine oxidase [flavin-containing] A (Homo sapiens (Human)) | BDBM10989 ((1R)-N-(prop-2-yn-1-yl)-2,3-dihydro-1H-inden-1-ami...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.34E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant human MAOA using kynuramine as substrate measured for 30 mins by fluorescence spectrophotometric assay | Citation and Details Article DOI: 10.1016/j.ejmech.2021.113183 BindingDB Entry DOI: 10.7270/Q21G0R19 | |||||||||||
| More data for this Ligand-Target Pair | |||||||||||||
