Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Aminopeptidase N' and Ligand = 'BDBM50415629'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aminopeptidase N (Homo sapiens (Human))	BDBM50415629 (CHEMBL1077583) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CN)C(C)C)C(=O)N[C@H]1Cc2c(CN(CC(=O)N[C@@H](Cc3ccccc3)C(O)=O)C1=O)[nH]c1ccccc21 |r| Show InChI InChI=1S/C44H55N7O8/c1-5-26(4)39(50-41(55)34(19-28-15-17-29(52)18-16-28)48-40(54)32(22-45)25(2)3)42(56)49-35-21-31-30-13-9-10-14-33(30)46-37(31)23-51(43(35)57)24-38(53)47-36(44(58)59)20-27-11-7-6-8-12-27/h6-18,25-26,32,34-36,39,46,52H,5,19-24,45H2,1-4H3,(H,47,53)(H,48,54)(H,49,56)(H,50,55)(H,58,59)/t26-,32-,34-,35-,36-,39-/m0/s1	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Vrije Universiteit Brussel Curated by ChEMBL					Assay Description Inhibition of catalytic activity of human aminopeptidase N transfected in HEK293 cells assessed as formation of p-nitroaniline				J Med Chem 52: 5612-8 (2009) Article DOI: 10.1021/jm900651p BindingDB Entry DOI: 10.7270/Q2TB185F
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