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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Aminopeptidase N' and Ligand = 'BDBM50415631'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Aminopeptidase N


(Homo sapiens (Human))		BDBM50415631
PNG
(CHEMBL1077585)
Show SMILES CCCC[C@@H](N)CC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@H]1Cc2c(CN(CC(=O)N[C@@H](Cc3ccccc3)C(O)=O)C1=O)[nH]c1ccccc21 |r|
Show InChI InChI=1S/C45H57N7O8/c1-4-6-14-30(46)23-39(54)48-35(21-29-17-19-31(53)20-18-29)42(56)51-41(27(3)5-2)43(57)50-36-24-33-32-15-10-11-16-34(32)47-38(33)25-52(44(36)58)26-40(55)49-37(45(59)60)22-28-12-8-7-9-13-28/h7-13,15-20,27,30,35-37,41,47,53H,4-6,14,21-26,46H2,1-3H3,(H,48,54)(H,49,55)(H,50,57)(H,51,56)(H,59,60)/t27-,30+,35-,36-,37-,41-/m0/s1
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Similars
Article
PubMed
 55.0n/an/an/an/an/an/an/an/a



Vrije Universiteit Brussel

Curated by ChEMBL


Assay Description
Inhibition of catalytic activity of human aminopeptidase N transfected in HEK293 cells assessed as formation of p-nitroaniline

J Med Chem 52: 5612-8 (2009)


Article DOI: 10.1021/jm900651p
BindingDB Entry DOI: 10.7270/Q2TB185F
More data for this
Ligand-Target Pair