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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Angiotensin II type 1a (AT-1a) receptor' and Ligand = 'BDBM50042739'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Angiotensin II type 1a (AT-1a) receptor


(RABBIT)
BDBM50042739
PNG
((2-Chloro-phenyl)-[4-(2-ethyl-5,7-dimethyl-imidazo...)
Show SMILES CCCc1cc(Cn2c(CC)nc3c(C)cc(C)nc23)cc(CCC)c1OC(C(O)=O)c1ccccc1Cl
Show InChI InChI=1S/C31H36ClN3O3/c1-6-11-22-16-21(18-35-26(8-3)34-27-19(4)15-20(5)33-30(27)35)17-23(12-7-2)28(22)38-29(31(36)37)24-13-9-10-14-25(24)32/h9-10,13-17,29H,6-8,11-12,18H2,1-5H3,(H,36,37)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Patents

PubMed
n/an/a 0.530n/an/an/an/an/an/a



Merck Research Laboratories

Curated by ChEMBL


Assay Description
Displacement of [1251][Sar1,IIe8]AII from rabbit aorta Angiotensin II receptor, type 1


J Med Chem 36: 3738-42 (1994)


BindingDB Entry DOI: 10.7270/Q2J1027W
More data for this
Ligand-Target Pair