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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Angiotensin II type 1a (AT-1a) receptor' and Ligand = 'BDBM50280332'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Angiotensin II type 1a (AT-1a) receptor


(Bos taurus)
BDBM50280332
PNG
(4,4-Diethyl-6-[2-oxo-prop-(E)-ylidene]-1-[2'-(1H-t...)
Show SMILES CCC1(CC)CC(=O)N(Cc2ccc(cc2)-c2ccccc2-c2nnn[nH]2)C(C1)=CC(C)=O |w:29.33|
Show InChI InChI=1S/C26H29N5O2/c1-4-26(5-2)15-21(14-18(3)32)31(24(33)16-26)17-19-10-12-20(13-11-19)22-8-6-7-9-23(22)25-27-29-30-28-25/h6-14H,4-5,15-17H2,1-3H3,(H,27,28,29,30)
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PC cid
PC sid
UniChem
Article
n/an/a 3.10E+3n/an/an/an/an/an/a



TBA

Curated by ChEMBL


Assay Description
Ability of the compound to displace [125I]- labelled [Sar1,Ileu8] from angiotensin II receptor of bovine adrenal cortex membranes


Bioorg Med Chem Lett 2: 1775-1779 (1992)


Article DOI: 10.1016/S0960-894X(00)80474-6
BindingDB Entry DOI: 10.7270/Q2NP24B9
More data for this
Ligand-Target Pair