Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Angiotensin-converting enzyme (Oryctolagus cuniculus) | BDBM7459 (2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.90E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
India Institute of Chemical Technology Curated by ChEMBL | Assay Description Inhibition of rabbit lung ACE assessed as reduction in hippuryl-histidyl-leucine substrate by colorimetric assay | Bioorg Med Chem 19: 4772-81 (2011) Article DOI: 10.1016/j.bmc.2011.06.085 BindingDB Entry DOI: 10.7270/Q27M089B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Angiotensin-converting enzyme (Oryctolagus cuniculus) | BDBM7459 (2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 2.90E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Calabria Curated by ChEMBL | Assay Description Inhibition of ACE in rabbit lung assessed as decrease in dansylglycine concentration after 5 mins by HPLC analysis | Bioorg Med Chem Lett 20: 1990-3 (2010) Article DOI: 10.1016/j.bmcl.2010.01.113 BindingDB Entry DOI: 10.7270/Q2G73DW4 | |||||||||||
More data for this Ligand-Target Pair |