new BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Anthrax Lethal Factor (LF)' and Ligand = 'BDBM11987'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Anthrax Lethal Factor (LF)


(Bacillus anthracis)
BDBM11987
PNG
(2-hydroxy-5-(5-{[(5Z)-2-imino-4-oxo-3-(1,3-thiazol...)
Show SMILES OC(=O)c1cc(ccc1O)-c1ccc(\C=C2/SC(=N)N(C2=O)c2nccs2)o1
Show InChI InChI=1S/C18H11N3O5S2/c19-17-21(18-20-5-6-27-18)15(23)14(28-17)8-10-2-4-13(26-10)9-1-3-12(22)11(7-9)16(24)25/h1-8,19,22H,(H,24,25)/b14-8-,19-17?
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
3.10E+3 -31.7 4.20E+3n/an/an/an/a7.227



Montana State University



Assay Description
For selected lead compounds from fluorescence-based high-throughput screening, Km and Vmax were calculated using the double-reciprocal Lineweaver-Bur...


J Med Chem 49: 5232-44 (2006)


Article DOI: 10.1021/jm0605132
BindingDB Entry DOI: 10.7270/Q20C4T19
More data for this
Ligand-Target Pair