Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Apoptosis regulator Bcl-2' and Ligand = 'BDBM177792'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM177792 (US9120791, Example 8 | US9603854, 8) Show SMILES Oc1ccc(cc1)N(C(=O)c1cc(-c2cc3OCOc3cc2C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)n2CCCCc12)c1ccc2NCCc2c1 Show InChI InChI=1S/C45H45N5O6/c51-35-11-8-32(9-12-35)50(33-10-13-39-30(22-33)14-15-46-39)45(53)38-23-41(48-16-4-3-7-40(38)48)36-24-42-43(56-28-55-42)25-37(36)44(52)49-26-31-6-2-1-5-29(31)21-34(49)27-47-17-19-54-20-18-47/h1-2,5-6,8-13,22-25,34,46,51H,3-4,7,14-21,26-28H2/t34-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD US Patent					Assay Description The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, at a final concentration of 2.50×10−8 M, is...				US Patent US9603854 (2017) BindingDB Entry DOI: 10.7270/Q2GX4DMT
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Mus musculus (Mouse))	BDBM177792 (US9120791, Example 8 | US9603854, 8) Show SMILES Oc1ccc(cc1)N(C(=O)c1cc(-c2cc3OCOc3cc2C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)n2CCCCc12)c1ccc2NCCc2c1 Show InChI InChI=1S/C45H45N5O6/c51-35-11-8-32(9-12-35)50(33-10-13-39-30(22-33)14-15-46-39)45(53)38-23-41(48-16-4-3-7-40(38)48)36-24-42-43(56-28-55-42)25-37(36)44(52)49-26-31-6-2-1-5-29(31)21-34(49)27-47-17-19-54-20-18-47/h1-2,5-6,8-13,22-25,34,46,51H,3-4,7,14-21,26-28H2/t34-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	7.4	n/a
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD US Patent					Assay Description The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, at a final concentration of 2.50×10−8 M, is...				US Patent US9120791 (2015) BindingDB Entry DOI: 10.7270/Q21N7ZWC
					More data for this Ligand-Target Pair