Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Apoptosis regulator Bcl-2' and Ligand = 'BDBM177797'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM177797 (US9120791, Example 15 | US9603854, 15) Show SMILES C[C@@H]1COCCN1C[C@@H]1Cc2ccccc2CN1C(=O)c1cc2OCOc2cc1-c1cc(C(=O)N(c2ccc(O)cc2)c2ccc3n(C)ccc3c2)c2CCCCn12 Show InChI InChI=1S/C47H47N5O6/c1-30-28-56-20-19-49(30)27-36-21-31-7-3-4-8-33(31)26-51(36)46(54)39-25-45-44(57-29-58-45)24-38(39)43-23-40(42-9-5-6-17-50(42)43)47(55)52(34-10-13-37(53)14-11-34)35-12-15-41-32(22-35)16-18-48(41)2/h3-4,7-8,10-16,18,22-25,30,36,53H,5-6,9,17,19-21,26-29H2,1-2H3/t30-,36+/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD US Patent					Assay Description The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, at a final concentration of 2.50×10−8 M, is...				US Patent US9603854 (2017) BindingDB Entry DOI: 10.7270/Q2GX4DMT
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Mus musculus (Mouse))	BDBM177797 (US9120791, Example 15 | US9603854, 15) Show SMILES C[C@@H]1COCCN1C[C@@H]1Cc2ccccc2CN1C(=O)c1cc2OCOc2cc1-c1cc(C(=O)N(c2ccc(O)cc2)c2ccc3n(C)ccc3c2)c2CCCCn12 Show InChI InChI=1S/C47H47N5O6/c1-30-28-56-20-19-49(30)27-36-21-31-7-3-4-8-33(31)26-51(36)46(54)39-25-45-44(57-29-58-45)24-38(39)43-23-40(42-9-5-6-17-50(42)43)47(55)52(34-10-13-37(53)14-11-34)35-12-15-41-32(22-35)16-18-48(41)2/h3-4,7-8,10-16,18,22-25,30,36,53H,5-6,9,17,19-21,26-29H2,1-2H3/t30-,36+/m1/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	7.4	n/a
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD US Patent					Assay Description The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, at a final concentration of 2.50×10−8 M, is...				US Patent US9120791 (2015) BindingDB Entry DOI: 10.7270/Q21N7ZWC
					More data for this Ligand-Target Pair