Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Apoptosis regulator Bcl-2' and Ligand = 'BDBM177869'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM177869 (US9120791, Example 95 | US9603854, 95) Show SMILES Cc1ccc(C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)c(c1)-c1cc(C(=O)N(c2ccc(O)cc2)c2ccc3n(C)ccc3c2)c2CCCCn12 Show InChI InChI=1S/C46H47N5O4/c1-31-10-16-39(45(53)50-29-34-8-4-3-7-32(34)26-37(50)30-48-21-23-55-24-22-48)40(25-31)44-28-41(43-9-5-6-19-49(43)44)46(54)51(35-11-14-38(52)15-12-35)36-13-17-42-33(27-36)18-20-47(42)2/h3-4,7-8,10-18,20,25,27-28,37,52H,5-6,9,19,21-24,26,29-30H2,1-2H3/t37-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD US Patent					Assay Description The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, at a final concentration of 2.50×10−8 M, is...				US Patent US9603854 (2017) BindingDB Entry DOI: 10.7270/Q2GX4DMT
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Mus musculus (Mouse))	BDBM177869 (US9120791, Example 95 | US9603854, 95) Show SMILES Cc1ccc(C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)c(c1)-c1cc(C(=O)N(c2ccc(O)cc2)c2ccc3n(C)ccc3c2)c2CCCCn12 Show InChI InChI=1S/C46H47N5O4/c1-31-10-16-39(45(53)50-29-34-8-4-3-7-32(34)26-37(50)30-48-21-23-55-24-22-48)40(25-31)44-28-41(43-9-5-6-19-49(43)44)46(54)51(35-11-14-38(52)15-12-35)36-13-17-42-33(27-36)18-20-47(42)2/h3-4,7-8,10-18,20,25,27-28,37,52H,5-6,9,19,21-24,26,29-30H2,1-2H3/t37-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	7.4	n/a
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD US Patent					Assay Description The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, at a final concentration of 2.50×10−8 M, is...				US Patent US9120791 (2015) BindingDB Entry DOI: 10.7270/Q21N7ZWC
					More data for this Ligand-Target Pair