Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Apoptosis regulator Bcl-2' and Ligand = 'BDBM177883'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM177883 (US9120791, Example 112 | US9603854, 112) Show SMILES COc1ccc(C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)c(c1)-c1cc(C(=O)N(c2ccccc2)c2ccc(O)cc2)c2CCCCn12 Show InChI InChI=1S/C43H44N4O5/c1-51-36-18-19-37(42(49)46-28-31-10-6-5-9-30(31)25-34(46)29-44-21-23-52-24-22-44)38(26-36)41-27-39(40-13-7-8-20-45(40)41)43(50)47(32-11-3-2-4-12-32)33-14-16-35(48)17-15-33/h2-6,9-12,14-19,26-27,34,48H,7-8,13,20-25,28-29H2,1H3/t34-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD US Patent					Assay Description The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, at a final concentration of 2.50×10−8 M, is...				US Patent US9603854 (2017) BindingDB Entry DOI: 10.7270/Q2GX4DMT
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Mus musculus (Mouse))	BDBM177883 (US9120791, Example 112 | US9603854, 112) Show SMILES COc1ccc(C(=O)N2Cc3ccccc3C[C@H]2CN2CCOCC2)c(c1)-c1cc(C(=O)N(c2ccccc2)c2ccc(O)cc2)c2CCCCn12 Show InChI InChI=1S/C43H44N4O5/c1-51-36-18-19-37(42(49)46-28-31-10-6-5-9-30(31)25-34(46)29-44-21-23-52-24-22-44)38(26-36)41-27-39(40-13-7-8-20-45(40)41)43(50)47(32-11-3-2-4-12-32)33-14-16-35(48)17-15-33/h2-6,9-12,14-19,26-27,34,48H,7-8,13,20-25,28-29H2,1H3/t34-/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	7.4	n/a
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD US Patent					Assay Description The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, at a final concentration of 2.50×10−8 M, is...				US Patent US9120791 (2015) BindingDB Entry DOI: 10.7270/Q21N7ZWC
					More data for this Ligand-Target Pair