Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Apoptosis regulator Bcl-2' and Ligand = 'BDBM177884'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apoptosis regulator Bcl-2 (Homo sapiens (Human))	BDBM177884 (US9120791, Example 113 | US9603854, 113) Show SMILES OC1CCn2c(C1)c(cc2-c1cc2OCOc2cc1C(=O)N1Cc2ccccc2C[C@H]1CN1CCOCC1)C(=O)N(c1ccccc1)c1ccc(O)cc1 Show InChI InChI=1S/C43H42N4O7/c48-33-12-10-31(11-13-33)47(30-8-2-1-3-9-30)43(51)37-22-39(45-15-14-34(49)21-38(37)45)35-23-40-41(54-27-53-40)24-36(35)42(50)46-25-29-7-5-4-6-28(29)20-32(46)26-44-16-18-52-19-17-44/h1-13,22-24,32,34,48-49H,14-21,25-27H2/t32-,34?/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD US Patent					Assay Description The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, at a final concentration of 2.50×10−8 M, is...				US Patent US9603854 (2017) BindingDB Entry DOI: 10.7270/Q2GX4DMT
					More data for this Ligand-Target Pair
Apoptosis regulator Bcl-2 (Mus musculus (Mouse))	BDBM177884 (US9120791, Example 113 | US9603854, 113) Show SMILES OC1CCn2c(C1)c(cc2-c1cc2OCOc2cc1C(=O)N1Cc2ccccc2C[C@H]1CN1CCOCC1)C(=O)N(c1ccccc1)c1ccc(O)cc1 Show InChI InChI=1S/C43H42N4O7/c48-33-12-10-31(11-13-33)47(30-8-2-1-3-9-30)43(51)37-22-39(45-15-14-34(49)21-38(37)45)35-23-40-41(54-27-53-40)24-36(35)42(50)46-25-29-7-5-4-6-28(29)20-32(46)26-44-16-18-52-19-17-44/h1-13,22-24,32,34,48-49H,14-21,25-27H2/t32-,34?/m0/s1	PDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	16	n/a	n/a	n/a	n/a	7.4	n/a
LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD US Patent					Assay Description The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, at a final concentration of 2.50×10−8 M, is...				US Patent US9120791 (2015) BindingDB Entry DOI: 10.7270/Q21N7ZWC
					More data for this Ligand-Target Pair