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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Apoptosis regulator Bcl-2' and Ligand = 'BDBM341040'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Apoptosis regulator Bcl-2


(Homo sapiens (Human))		BDBM341040
PNG
(1-(5-Chloro-2-{[(3S)-3-[(4-methylpiperazin-1-yl)me...)
Show SMILES CN1CCN(C[C@@H]2Cc3ccccc3CN2C(=O)c2ccc(Cl)cc2-n2cc(C(=O)N(c3ccc(O)cc3)c3ccc4n(C)ccc4c3)c3ccccc23)CC1
Show InChI InChI=1S/C46H43ClN6O3/c1-48-21-23-50(24-22-48)29-37-25-31-7-3-4-8-33(31)28-51(37)45(55)40-17-11-34(47)27-44(40)52-30-41(39-9-5-6-10-43(39)52)46(56)53(35-12-15-38(54)16-13-35)36-14-18-42-32(26-36)19-20-49(42)2/h3-20,26-27,30,37,54H,21-25,28-29H2,1-2H3/t37-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
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PC cid
PC sid
UniChem
US Patent
n/an/a 3.30n/an/an/an/an/an/a



LES LABORATOIRES SERVIER; VERNALIS (R&D) LTD

US Patent


Assay Description
Method A:The fluorescence polarisation tests were carried out on microplates (384 wells). The Bcl-2 protein, labelled (histag-Bcl-2 such that Bcl-2 c...

US Patent US9765056 (2017)


BindingDB Entry DOI: 10.7270/Q2T72KJF
More data for this
Ligand-Target Pair