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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Apoptosis regulator Bcl-2' and Ligand = 'BDBM50181874'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Apoptosis regulator Bcl-2


(Homo sapiens (Human))		BDBM50181874
PNG
(CHEMBL201670 | N-[2'-methoxy-4'-(3-morpholin-4-yl-...)
Show SMILES COc1cc(CCC(=O)N2CCOCC2)ccc1-c1ccc(cc1)C(=O)NS(=O)(=O)c1ccc(NCCSc2ccccc2)c(c1)[N+]([O-])=O
Show InChI InChI=1S/C35H36N4O8S2/c1-46-33-23-25(8-16-34(40)38-18-20-47-21-19-38)7-14-30(33)26-9-11-27(12-10-26)35(41)37-49(44,45)29-13-15-31(32(24-29)39(42)43)36-17-22-48-28-5-3-2-4-6-28/h2-7,9-15,23-24,36H,8,16-22H2,1H3,(H,37,41)
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Similars
Article
PubMed
 366n/an/an/an/an/an/an/an/a



Abbott Laboratories

Curated by ChEMBL


Assay Description
Binding affinity to Bcl2 by fluorescence polarization assay

J Med Chem 49: 1165-81 (2006)


Article DOI: 10.1021/jm050754u
BindingDB Entry DOI: 10.7270/Q2VM4BT0
More data for this
Ligand-Target Pair