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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Apoptosis regulator Bcl-2' and Ligand = 'BDBM50195322'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Apoptosis regulator Bcl-2


(Homo sapiens (Human))		BDBM50195322
PNG
(CHEMBL3971723)
Show SMILES [O-][N+](=O)c1cc(ccc1NCCSc1ccccc1)S(=O)(=O)NC(=O)c1ccc(NC(=O)\C=C\c2ccccc2C(F)(F)F)cc1
Show InChI InChI=1S/C31H25F3N4O6S2/c32-31(33,34)26-9-5-4-6-21(26)12-17-29(39)36-23-13-10-22(11-14-23)30(40)37-46(43,44)25-15-16-27(28(20-25)38(41)42)35-18-19-45-24-7-2-1-3-8-24/h1-17,20,35H,18-19H2,(H,36,39)(H,37,40)/b17-12+
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Similars
Article
PubMed
 1.70E+3n/an/an/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of 5-FAM-Bid peptide binding to Bcl-2 (unknown origin) by fluorescence polarization assay

Bioorg Med Chem Lett 26: 5207-5211 (2016)


Article DOI: 10.1016/j.bmcl.2016.09.061
BindingDB Entry DOI: 10.7270/Q2PN97K9
More data for this
Ligand-Target Pair