BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Apoptosis regulator Bcl-2' and Ligand = 'BDBM50261487'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Apoptosis regulator Bcl-2


(Homo sapiens (Human))		BDBM50261487
PNG
(CHEMBL4098468)
Show SMILES COc1ccc(cc1)S(=O)(=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)Cc1c(C)n(-c2ccc(cc2)-c2ccccc2)c2ccc(OC)cc12 |r|
Show InChI InChI=1S/C40H37N3O6S/c1-27-35(36-25-33(49-3)20-23-38(36)43(27)31-16-14-30(15-17-31)29-12-8-5-9-13-29)26-39(44)41-37(24-28-10-6-4-7-11-28)40(45)42-50(46,47)34-21-18-32(48-2)19-22-34/h4-23,25,37H,24,26H2,1-3H3,(H,41,44)(H,42,45)/t37-/m0/s1
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
Article
PubMed
 470n/an/an/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of 5-FAM-Bid-BH3 peptide binding to Bcl2 (unknown origin) pre-incubated for 30 mins followed by further incubation with 5-FAM-Bid-BH3 pept...

Bioorg Med Chem 25: 5548-5556 (2017)


Article DOI: 10.1016/j.bmc.2017.08.024
BindingDB Entry DOI: 10.7270/Q2FX7CX8
More data for this
Ligand-Target Pair