Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM50336580 (CHEMBL1672071 | Isopropyl-3-(4-isopropylphenoxy)-8...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 252 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Dalian University of Technology Curated by ChEMBL | Assay Description Displacement of FAM-Bid peptide from human recombinant Bcl2 after 30 mins by by competitive fluorescence polarization assay | Eur J Med Chem 46: 3909-16 (2011) Article DOI: 10.1016/j.ejmech.2011.05.062 BindingDB Entry DOI: 10.7270/Q2MK6D8W | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Apoptosis regulator Bcl-2 (Homo sapiens (Human)) | BDBM50336580 (CHEMBL1672071 | Isopropyl-3-(4-isopropylphenoxy)-8...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 739 | n/a | n/a | n/a | n/a | n/a | n/a |
Dalian University of Technology Curated by ChEMBL | Assay Description Binding affinity to human Bcl-2 (unknown origin) by biotin-Bim displacement based ELISA | Bioorg Med Chem 21: 11-20 (2012) Article DOI: 10.1016/j.bmc.2012.11.008 BindingDB Entry DOI: 10.7270/Q25X2B7H | |||||||||||
More data for this Ligand-Target Pair |