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Found 1 hit Enz. Inhib. hit(s) with Target = 'Apoptosis regulator Bcl-2' and Ligand = 'BDBM50424212'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Apoptosis regulator Bcl-2


(Homo sapiens (Human))		BDBM50424212
PNG
(CHEMBL2312483)
Show SMILES O=c1nc2c3cccc4c(ccc(c2c1NCCCc1ccccc1)c34)N1CCSCC1
Show InChI InChI=1S/C27H25N3OS/c31-27-26(28-13-5-8-18-6-2-1-3-7-18)24-20-11-12-22(30-14-16-32-17-15-30)19-9-4-10-21(23(19)20)25(24)29-27/h1-4,6-7,9-12H,5,8,13-17H2,(H,28,29,31)
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Similars
Article
PubMed
n/an/a 49n/an/an/an/an/an/a



Dalian University of Technology

Curated by ChEMBL


Assay Description
Binding affinity to human Bcl-2 (unknown origin) by biotin-Bim displacement based ELISA

Bioorg Med Chem 21: 11-20 (2012)


Article DOI: 10.1016/j.bmc.2012.11.008
BindingDB Entry DOI: 10.7270/Q25X2B7H
More data for this
Ligand-Target Pair