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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Arginase-1' and Ligand = 'BDBM290384'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Arginase-1


(Homo sapiens (Human))
BDBM290384
PNG
((3R,4S)-1-((1H-imidazol-4-yl)methyl)-3-amino-4-(3-...)
Show SMILES N[C@]1(CN(Cc2c[nH]cn2)C[C@@H]1CCCB(O)O)C(O)=O |r|
PDB
MMDB

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KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 125n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...


Citation and Details

BindingDB Entry DOI: 10.7270/Q289193N
More data for this
Ligand-Target Pair
Arginase-1


(Homo sapiens (Human))
BDBM290384
PNG
((3R,4S)-1-((1H-imidazol-4-yl)methyl)-3-amino-4-(3-...)
Show SMILES N[C@]1(CN(Cc2c[nH]cn2)C[C@@H]1CCCB(O)O)C(O)=O |r|
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a<250n/an/an/an/a7.425



Mars, Incorporated

US Patent


Assay Description
Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...


US Patent US10098902 (2018)


BindingDB Entry DOI: 10.7270/Q2319XXK
More data for this
Ligand-Target Pair