Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'Arginase-1' and Ligand = 'BDBM290416'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Arginase-1 (Homo sapiens (Human))	BDBM290416 ((3R,4S)-3-amino-1-(2-(biphenyl-4-ylamino)ethyl)-4-...) Show SMILES N[C@]1(CN(CCNc2ccc(cc2)-c2ccccc2)C[C@@H]1CCCB(O)O)C(O)=O |r| Show InChI InChI=1S/C22H30BN3O4/c24-22(21(27)28)16-26(15-19(22)7-4-12-23(29)30)14-13-25-20-10-8-18(9-11-20)17-5-2-1-3-6-17/h1-3,5-6,8-11,19,25,29-30H,4,7,12-16,24H2,(H,27,28)/t19-,22-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	125	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				Citation and Details BindingDB Entry DOI: 10.7270/Q289193N
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM290416 ((3R,4S)-3-amino-1-(2-(biphenyl-4-ylamino)ethyl)-4-...) Show SMILES N[C@]1(CN(CCNc2ccc(cc2)-c2ccccc2)C[C@@H]1CCCB(O)O)C(O)=O |r| Show InChI InChI=1S/C22H30BN3O4/c24-22(21(27)28)16-26(15-19(22)7-4-12-23(29)30)14-13-25-20-10-8-18(9-11-20)17-5-2-1-3-6-17/h1-3,5-6,8-11,19,25,29-30H,4,7,12-16,24H2,(H,27,28)/t19-,22-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<250	n/a	n/a	n/a	n/a	7.4	25
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10098902 (2018) BindingDB Entry DOI: 10.7270/Q2319XXK
					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM290416 ((3R,4S)-3-amino-1-(2-(biphenyl-4-ylamino)ethyl)-4-...) Show SMILES N[C@]1(CN(CCNc2ccc(cc2)-c2ccccc2)C[C@@H]1CCCB(O)O)C(O)=O |r| Show InChI InChI=1S/C22H30BN3O4/c24-22(21(27)28)16-26(15-19(22)7-4-12-23(29)30)14-13-25-20-10-8-18(9-11-20)17-5-2-1-3-6-17/h1-3,5-6,8-11,19,25,29-30H,4,7,12-16,24H2,(H,27,28)/t19-,22-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Mars, Incorporated US Patent					Assay Description Inhibition of arginase I (ARG I) and arginase II (ARG II) by Formula I or Formula II compounds is followed spectrophotometrically at 530 nm. The comp...				US Patent US10603330 (2020) BindingDB Entry DOI: 10.7270/Q2WD43K6
					More data for this Ligand-Target Pair