Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Arginase-1 (Bos taurus) | BDBM50230418 (CHEMBL260629 | N(gamma)-hydroxy-L-arginine | N-OME...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid UniChem Similars | MMDB Article PubMed | 3.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Christian-Albrechts-University of Kiel Curated by ChEMBL | Assay Description Inhibition of bovine liver arginase | Bioorg Med Chem 16: 2305-12 (2008) Article DOI: 10.1016/j.bmc.2007.11.066 BindingDB Entry DOI: 10.7270/Q2KW5GXN | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Rattus norvegicus) | BDBM50230418 (CHEMBL260629 | N(gamma)-hydroxy-L-arginine | N-OME...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid UniChem Similars | MMDB Article PubMed | n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of rat Arg1 at pH 7.4 | Citation and Details Article DOI: 10.1016/j.bmc.2020.115658 BindingDB Entry DOI: 10.7270/Q2WS8XZC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Arginase-1 (Homo sapiens (Human)) | BDBM50230418 (CHEMBL260629 | N(gamma)-hydroxy-L-arginine | N-OME...) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MMDB PC cid PC sid UniChem Similars | MMDB Article PubMed | n/a | n/a | n/a | 3.60E+3 | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Binding affinity to human Arg1 at pH 8.5 | Citation and Details Article DOI: 10.1016/j.bmc.2020.115658 BindingDB Entry DOI: 10.7270/Q2WS8XZC | |||||||||||
More data for this Ligand-Target Pair |