Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Arginase-1 (Homo sapiens (Human)) | BDBM50427910 (CHEMBL2326096) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 260 | n/a | n/a | n/a | n/a | n/a | n/a |
Institutes for Pharmaceutical Discovery , LLC Curated by ChEMBL | Assay Description Inhibition of human recombinant full length arginase I overexpressed in Escherichia coli BL21(DE3) assessed as inhibition of urea formation after 60 ... | J Med Chem 56: 2568-80 (2013) Article DOI: 10.1021/jm400014c BindingDB Entry DOI: 10.7270/Q2BC40WP | |||||||||||
More data for this Ligand-Target Pair |