Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Atrial natriuretic peptide receptor 3' and Ligand = 'BDBM50254095'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Atrial natriuretic peptide receptor 3 (Homo sapiens (Human))	BDBM50254095 (CHEMBL4084171) Show SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@@H](C)NC(=O)[C@H](CC1CCCCC1)NC(=O)[C@H]1CCCN1C(=O)[C@H](CO)NC(=O)[C@@H](Cc1ccccc1)NC(C)=O)[C@@H](C)CC)C(=O)NCC(N)=O |r| Show InChI InChI=1S/C62H98N16O16/c1-7-34(3)50(59(92)67-31-47(63)81)75-53(86)40(22-15-25-66-62(64)65)71-56(89)43(30-49(83)84)73-60(93)51(35(4)8-2)76-58(91)45-23-16-26-77(45)48(82)32-68-52(85)36(5)69-54(87)42(29-39-20-13-10-14-21-39)72-57(90)46-24-17-27-78(46)61(94)44(33-79)74-55(88)41(70-37(6)80)28-38-18-11-9-12-19-38/h9,11-12,18-19,34-36,39-46,50-51,79H,7-8,10,13-17,20-33H2,1-6H3,(H2,63,81)(H,67,92)(H,68,85)(H,69,87)(H,70,80)(H,71,89)(H,72,90)(H,73,93)(H,74,88)(H,75,86)(H,76,91)(H,83,84)(H4,64,65,66)/t34-,35-,36+,40-,41+,42-,43-,44-,45-,46+,50-,51-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.190	n/a	n/a	n/a	n/a	n/a	n/a
Takeda Pharmaceutical Company Ltd Curated by ChEMBL					Assay Description Displacement of [125I]-human ANP from His-tagged and Fc fragment containing human NPR-3 extracellular domain expressed in FreeStyle 293 cells incubat...				Bioorg Med Chem Lett 27: 3542-3545 (2017) Article DOI: 10.1016/j.bmcl.2017.05.061 BindingDB Entry DOI: 10.7270/Q2F19241
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