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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Aurora kinase A' and Ligand = 'BDBM25687'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Aurora kinase A


(Homo sapiens (Human))		BDBM25687
PNG
(4-[(5-bromo-1,3-thiazol-2-yl)amino]-N-[2-(diethyla...)
Show SMILES CCN(CC)CCNC(=O)c1ccc(Nc2ncc(Br)s2)cc1
Show InChI InChI=1S/C16H21BrN4OS/c1-3-21(4-2)10-9-18-15(22)12-5-7-13(8-6-12)20-16-19-11-14(17)23-16/h5-8,11H,3-4,9-10H2,1-2H3,(H,18,22)(H,19,20)
PDB
MMDB

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Similars
Article
PubMed
n/an/a 4.52E+3n/an/an/an/an/an/a



Novartis



Assay Description
The biochemical activity of compounds was determined by incubation with Aurora A and substrates in the presence ATP/[gamma-33P] ATP. After incubatio...

ACS Chem Biol 3: 180-92 (2008)


Article DOI: 10.1021/cb700200w
BindingDB Entry DOI: 10.7270/Q2HX1B03
More data for this
Ligand-Target Pair