Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Aurora kinase A' and Ligand = 'BDBM50181549'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Homo sapiens (Human))	BDBM50181549 (CHEMBL203422 | N-[3-(dimethylamino)phenyl]-2-{2-[(...) Show SMILES COc1cc2c(Nc3ncc(CC(=O)Nc4cccc(c4)N(C)C)s3)ncnc2cc1OCCCN1CCC[C@H]1CO Show InChI InChI=1S/C30H37N7O4S/c1-36(2)21-8-4-7-20(13-21)34-28(39)14-23-17-31-30(42-23)35-29-24-15-26(40-3)27(16-25(24)32-19-33-29)41-12-6-11-37-10-5-9-22(37)18-38/h4,7-8,13,15-17,19,22,38H,5-6,9-12,14,18H2,1-3H3,(H,34,39)(H,31,32,33,35)/t22-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	483	n/a	n/a	n/a	n/a	n/a	n/a
Centre de Recherches Curated by ChEMBL					Assay Description In vitro inhibition constant for Aurora-A				J Med Chem 49: 955-70 (2006) Article DOI: 10.1021/jm050786h BindingDB Entry DOI: 10.7270/Q24J0FXV
					More data for this Ligand-Target Pair