Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Aurora kinase A' and Ligand = 'BDBM50224736'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Homo sapiens (Human))	BDBM50224736 (2-(4-(pyrrolidin-1-yl)phenyl)-3H-imidazo[4,5-b]pyr...) Show SMILES C1CCN(C1)c1ccc(cc1)-c1nc2ncccc2[nH]1 Show InChI InChI=1S/C16H16N4/c1-2-11-20(10-1)13-7-5-12(6-8-13)15-18-14-4-3-9-17-16(14)19-15/h3-9H,1-2,10-11H2,(H,17,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Jinan University Curated by ChEMBL					Assay Description Inhibition of Aurora A				Eur J Med Chem 46: 77-94 (2010) Article DOI: 10.1016/j.ejmech.2010.10.017 BindingDB Entry DOI: 10.7270/Q25X296N
					More data for this Ligand-Target Pair
Aurora kinase A (Homo sapiens (Human))	BDBM50224736 (2-(4-(pyrrolidin-1-yl)phenyl)-3H-imidazo[4,5-b]pyr...) Show SMILES C1CCN(C1)c1ccc(cc1)-c1nc2ncccc2[nH]1 Show InChI InChI=1S/C16H16N4/c1-2-11-20(10-1)13-7-5-12(6-8-13)15-18-14-4-3-9-17-16(14)19-15/h3-9H,1-2,10-11H2,(H,17,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Cancer Research Curated by ChEMBL					Assay Description Inhibition of aurora A kinase				Bioorg Med Chem Lett 17: 6567-71 (2007) Article DOI: 10.1016/j.bmcl.2007.09.076 BindingDB Entry DOI: 10.7270/Q27D2TVT
					More data for this Ligand-Target Pair