Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Aurora kinase A' and Ligand = 'BDBM50245471'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aurora kinase A (Homo sapiens (Human))	BDBM50245471 (4-amino-6-(4-(benzyloxy)-3-chlorophenylamino)-N'-(...) Show SMILES Nc1ncnc(Nc2ccc(OCc3ccccc3)c(Cl)c2)c1C(=O)NNC(=O)CCN1CCOCC1 Show InChI InChI=1S/C25H28ClN7O4/c26-19-14-18(6-7-20(19)37-15-17-4-2-1-3-5-17)30-24-22(23(27)28-16-29-24)25(35)32-31-21(34)8-9-33-10-12-36-13-11-33/h1-7,14,16H,8-13,15H2,(H,31,34)(H,32,35)(H3,27,28,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Johnson & Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Inhibition of Aurora A (unknown origin)				Bioorg Med Chem Lett 18: 4896-9 (2008) Article DOI: 10.1016/j.bmcl.2008.07.057 BindingDB Entry DOI: 10.7270/Q2NS0TPB
					More data for this Ligand-Target Pair