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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Aurora kinase A' and Ligand = 'BDBM50264613'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Aurora kinase A


(Homo sapiens (Human))		BDBM50264613
PNG
(7-(5-(benzyloxy)-1H-indol-2-yl)isoindolin-1-one | ...)
Show SMILES O=C1NCc2cccc(-c3cc4cc(OCc5ccccc5)ccc4[nH]3)c12
Show InChI InChI=1S/C23H18N2O2/c26-23-22-16(13-24-23)7-4-8-19(22)21-12-17-11-18(9-10-20(17)25-21)27-14-15-5-2-1-3-6-15/h1-12,25H,13-14H2,(H,24,26)
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Article
PubMed
n/an/a 2.12E+4n/an/an/an/an/an/a



Johnson & Johnson Pharmaceutical Research and Development

Curated by ChEMBL


Assay Description
Inhibition of Aurora A (unknown origin)

Bioorg Med Chem Lett 18: 5130-3 (2008)


Article DOI: 10.1016/j.bmcl.2008.07.090
BindingDB Entry DOI: 10.7270/Q2RF5TVZ
More data for this
Ligand-Target Pair